Global Trends and Research Progress of Photodynamic Therapy in Skin Cancer: A Bibliometric Analysis and Literature Review

被引:31
作者
Sun, Jiachen [1 ]
Zhao, Hongqing [1 ]
Fu, Lin [2 ]
Cui, Jing [3 ]
Yang, Yuguang [1 ]
机构
[1] Chinese Peoples Liberat Army Gen Hosp, Med Ctr 4, Dept Dermatol, Beijing, Peoples R China
[2] Chinese Acad Med Sci & Peking Union Med Coll, Plast Surg Hosp, Beijing, Peoples R China
[3] Anhui Med Univ, Navy Clin Coll, Sch Clin Med 5, Hefei, Peoples R China
关键词
photodynamic therapy; photosensitizers; skin cancer; bibliometric; BASAL-CELL CARCINOMA; VULVAR PAGETS-DISEASE; METHYL AMINOLEVULINATE; ENDOGENOUS PROTOPORPHYRIN; ACTINIC KERATOSES; SINGLE-BLIND; FLUOROURACIL; EFFICACY; IMIQUIMOD; TUMOR;
D O I
10.2147/CCID.S401206
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Background: Based on photochemical reactions through the combined use of light and photosensitizers, photodynamic therapy (PDT) is gaining popularity for the treatment of skin cancer. Various photosensitizers and treatment regimens are continuously being developed for enhancing the efficacy of PDT on skin cancer. Reviewing the development history of PDT on skin cancer, and summarizing its development direction and research status, is conducive to the further research. Methods: To evaluate the research trends and map knowledge structure, all publications covering PDT on skin cancer were retrieved and extracted from Web of Science database. We applied VOSviewer and CiteSpace softwares to evaluate and visualize the countries, institutes, authors, keywords and research trends. Literature review was performed for the analysis of the research status of PDT on skin cancer. Results: A total of 2662 publications were identified. The elements, mechanism, pros and cons, representative molecular photo-sensitizers, current challenges and research progress of PDT on skin cancer were reviewed and summarized. Conclusion: This study provides a comprehensive display of the field of PDT on skin cancer, which will help researchers further explore the mechanism and application of PDT more effectively and intuitively.
引用
收藏
页码:479 / 498
页数:20
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