Trends in the prevalence of cognitive impairment at old age in China, 2002-2018

被引：4

作者：

Chen, Huashuai ^{[1
]}

Ye, Kaisy Xinhong ^{[2
,3
]}

Feng, Qiushi ^{[4
]}

Cao, Kai ^{[5
,6
]}

Yu, Jintai ^{[7
]}

Li, Chunbo ^{[8
,9
]}

Zhang, Can ^{[10
]}

Yu, Lirong ^{[11
]}

Maier, Andrea Britta ^{[5
,6
,12
,13
,14
]}

Langa, Kenneth M. ^{[15
]}

Qiu, Chengxuan ^{[16
]}

Zeng, Yi ^{[17
,18
,19
]}

Feng, Lei ^{[2
,3
,14
]}

机构：

[1] Xiangtan Univ, Business Sch, Xiangtan, Peoples R China

[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Psychol Med, NUHS Tower Block Level 9 1E Kent Ridge Rd, Singapore 119228, Singapore

[3] Natl Univ Hlth Syst, AgeSingapore, Ctr Hlth Longev, Singapore, Singapore

[4] Natl Univ Singapore, Fac Arts & Social Sci, Dept Sociol & Anthropol, Singapore, Singapore

[5] East China Normal Univ, Minist Educ, Key Lab Geog Informat Sci, Shanghai, Peoples R China

[6] East China Normal Univ, Sch Geog Sci, Shanghai, Peoples R China

[7] Fudan Univ, Huashan Hosp, Shanghai, Peoples R China

[8] Shanghai Jiao Tong Univ, Shanghai Mental Hlth Ctr, Sch Med, Shanghai, Peoples R China

[9] Shanghai Jiao Tong Univ, Inst Psychol & Behav Sci, Shanghai, Peoples R China

[10] Harvard Med Sch, Massachusetts Gen Hosp, McCance Ctr Brain Hlth, Genet & Aging Res Unit,Dept Neurol, Boston, MA USA

[11] Weifang Med Univ, Sch Nursing, Weifang, Peoples R China

[12] Vrije Univ Amsterdam, Dept Human Movement Sci, AgeAmsterdam, Amsterdam Movement Sci, Amsterdam, Netherlands

[13] Univ Melbourne, Royal Melbourne Hosp, Dept Med & Aged Care, AgeMelbourne, Parkville, Vic, Australia

[14] Natl Univ Singapore, Yong Loo Lin Sch Med, Healthy Longev Translat Res Program, Singapore, Singapore

[15] Univ Michigan, Dept Internal Med, Ann Arbor, MI USA

[16] Stockholm Univ, Karolinska Inst, Dept Neurobiol Care Sci & Soc, Aging Res Ctr, Solna, Sweden

[17] Peking Univ, Natl Sch Dev, Ctr Hlthy Aging & Dev Studies, Beijing, Peoples R China

[18] Duke Univ, Sch Med, Ctr Study Aging & Human Dev, Box 3003,BUSSE Bldg, Durham, NC 27710 USA

[19] Duke Univ, Sch Med, Geriatr Div, Box 3003,BUSSE Bldg, Durham, NC 27710 USA

来源：

ALZHEIMERS & DEMENTIA | 2024年 / 20卷 / 02期

基金：

美国国家卫生研究院; 英国医学研究理事会; 瑞典研究理事会; 国家重点研发计划;

关键词：

aged; China; cognitive impairment; dementia; prevalence; MINI-MENTAL-STATE; DEMENTIA PREVENTION; ALZHEIMERS-DISEASE; POPULATIONS; BURDEN; HEALTH; IMPACT; INCOME;

D O I：

10.1002/alz.13545

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

INTRODUCTION: China has the world's largest number of older adults with cognitive impairment (CI). We aimed to examine secular trends in the prevalence of CI in China from 2002 to 2018. METHODS: Generalized estimating equations (GEE) was used to assess changes in CI trend in 44,154 individuals (72,027 observations) aged 65 to 105 years old. RESULTS: The prevalence of CI increased from 2002 to 2008 and then decreased until 2018. The age-standardized prevalence increased from 25.7% in 2002, 26.1% in 2005, to 28.2% in 2008, then decreased to 26.0% in 2011, 25.3% in 2014, and 24.9% in 2018. Females and those >= 80 years old had greater CI prevalence. DISCUSSION: The prevalence of CI showed an inverted U shape from early 2000s to late 2010s with a peak in 2008. Follow-up studies are needed to confirm the decreasing trend after 2008 and examine the contributing factors and underlying mechanisms of this trend.

引用

页码：1387 / 1396

页数：10

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