Tafasitamab and lenalidomide in large B-cell lymphoma: real-world outcomes in a multicenter retrospective study

被引:22
作者
Qualls, David A.
Lambert, Nicholas [1 ,2 ]
Caimi, Paolo F. [3 ]
Merrill, Mwanasha [4 ]
Pullarkat, Priyanka [5 ]
Godby, Richard C. [6 ]
Bond, David A. [6 ]
Wehmeyer, Graham T. [9 ,10 ]
Romancik, Jason [11 ]
Amoozgar, Behzad [12 ]
Leslie, Lori [11 ]
Nastoupil, Loretta J. [1 ,13 ,14 ]
Crombie, Jennifer L. [4 ]
Abramson, Jeremy S. [4 ]
Khurana, Arushi [6 ]
Nowakowski, Grzegorz S. [5 ]
Maddocks, Kami [7 ,8 ]
Rutherford, Sarah C. [9 ,10 ]
Kahl, Brad [12 ]
Okwali, Michelle [1 ]
Buege, Michael J. [1 ]
Seshan, Venkatraman [1 ]
Batlevi, Connie L. [1 ]
Salles, Gilles [1 ,15 ,16 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Lymphoma Serv, Div Hematol Malignancies, New York, NY 10065 USA
[2] Baylor Coll Med, Dept Med, Houston, TX USA
[3] Cleveland Clin Fdn, Taussig Canc Inst, Dept Hematol & Med Oncol, Cleveland, OH USA
[4] Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA
[5] Massachusetts Gen Hosp, Div Hematol Oncol, Boston, MA USA
[6] Mayo Clin, Div Hematol & Oncol, Dept Internal Med, Rochester, MN USA
[7] Ohio State Univ, James Canc Hosp, Columbus, OH USA
[8] Ohio State Univ, Solove Res Inst, Columbus, OH USA
[9] Weill Cornell Med, Dept Med, Meyer Canc Ctr, New York, NY USA
[10] New York Presbyterian Hosp, New York, NY USA
[11] Emory Univ, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA USA
[12] Washington Univ, Sch Med, Dept Med, St Louis, MO USA
[13] Hackensack Univ, Med Ctr, John Theurer Canc Ctr, Lymphoma Div, Hackensack, NJ USA
[14] Univ Texas MD Anderson Canc Ctr, Dept Lymphoma & Myeloma, Houston, TX USA
[15] Weill Cornell Med Coll, New York, NY 10065 USA
[16] Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10065 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1182/blood.2023021274
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In this real-world evaluation of tafasitamab-lenalidomide (TL) in relapsed or refractory LBCL, patients receiving TL had higher rates of comorbidities and high-risk disease characteristics, and substantially lower progression-free survival and overall survival, compared with the L-MIND registration clinical trial for TL. © 2023 The American Society of Hematology
引用
收藏
页码:2327 / 2331
页数:5
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