l-Tyrosine-based biocompatible low-toxic substrate of peroxyoxalate chemiluminescent reaction

被引：1
|
作者：
Dets, Elizabeth A. [1 ]
Iakimov, Nikolai P. [1 ]
Grozdova, Irina D. [1 ]
Melik-Nubarov, Nikolay S. [1 ]
机构：
[1] Moscow MV Lomonosov State Univ, Dept Chem, Moscow 119991, Russia
来源：
MENDELEEV COMMUNICATIONS | 2023年 / 33卷 / 06期
基金：
俄罗斯科学基金会;
关键词：
peroxyoxalate chemiluminescent reaction; poly-L-lactide-PEG amphiphilic copolymers; L-tyrosine; bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate; chemo-induced PDT; micelles; NANOPARTICLES; COPOLYMERS; OXALATE;
D O I：
10.1016/j.mencom.2023.10.018
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We synthesized a biocompatible substrate of the peroxy-oxalate chemiluminescent reaction on the basis ofN-benzoyl-l-tyrosine ethyl ester. Its ability to interact with hydrogen peroxide was evaluated by light emission in the presence of a perylene activator. Its cytotoxicity is three times less than that of bis[2,4,5-trichloro-6-(pentyloxycarbonyl)phenyl] oxalate (CPPO).
引用
收藏
页码：793 / 795
页数：3
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