Flavone C-glycosides from Dendrobium gratiosissimum

被引：0

作者：

Song, Zhijun ^{[1
]}

Liu, Jimei ^{[1
]}

Li, Changkang ^{[1
]}

Sun, Xincheng ^{[1
]}

Chen, Dawei ^{[1
]}

Chen, Ridao ^{[1
]}

Xie, Kebo ^{[1
]}

Han, Yaotian ^{[1
]}

Dai, Jungui ^{[1
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, State Key Lab Bioact Subst & Funct Nat Med, CAMS Key Lab Enzyme & Biocatalysis Nat Drug, Beijing 100050, Peoples R China

来源：

PHYTOCHEMISTRY LETTERS | 2023年 / 54卷

关键词：

Dendrobium gratiosissimum; Orchidaceae; Flavone C -glycosides; Cytotoxicity;

D O I：

10.1016/j.phytol.2023.03.003

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A phytochemical investigation of Dendrobium gratiosissimum Rchb. f. (Orchidaceae) led to the isolation of four new flavone C-glycosides (1-4) together with four known ones (5-8). The chemical structures of the new flavone C-glycosides (1-4) were elucidated by extensive spectroscopic data analysis including 1D- and 2D NMR, HR-ESI-MS, ESI-MS2 and careful comparison of the sugar unit spectroscopic data with those of reported in the literature. Biological assay revealed that compounds 6 and 7 showed moderate cytotoxicity against the human tumor cell line HepG2 by suppressing cell viability with an inhibition rate of 76.7 % and 79.6 % at 10.0 mu M, respectively.

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收藏

页码：158 / 162

页数：5

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