SARS-CoV-2 effects on male reproduction: should men be worried??

被引：5
作者：
Farsimadan, Marziye [1 ]
Motamedifar, Mohammad [2 ]
机构：
[1] Univ Guilan, Fac Sci, Dept Biol, Rasht 4193833697, Iran
[2] Shiraz Univ Med Sci, Shiraz Med Sch, Dept Bacteriol & Virol, Shiraz, Iran
来源：
HUMAN FERTILITY | 2023年 / 26卷 / 01期
关键词：
SARS-coronavirus; 2; male reproduction; semen; sperm; male infertility; male reproductive health; BLOOD-TESTIS BARRIER; COVID-19; PATIENTS; ZIKA VIRUS; SEMEN; CORONAVIRUS; INFECTION; CYTOKINES; EXPRESSION; PROSTATE; TMPRSS2;
D O I：
10.1080/14647273.2021.1962986
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has placed a global challenge on both healthcare and society. So far, studies have shown that men are more prone to become ill than women and are more likely to die compared to female patients. Higher rates of positive cases and fatality in men than women have drawn the attention of scientists to investigate the possible impacts of SARS-CoV-2 on the male reproductive system. In this review, we tried to summarise so far findings on the effect of the SARS-CoV-2 on the male reproductive function to further assess the potential risks of this novel coronavirus on male reproductive health.
引用
收藏
页码：50 / 60
页数：11
相关论文
共 85 条
[1]   The Cellular Impact of the ZIKA Virus on Male Reproductive Tract Immunology and Physiology [J].
Almeida, Raquel das Neves ;
Braz-de-Melo, Heloisa Antoniella ;
Santos, Igor de Oliveira ;
Correa, Rafael ;
Kobinger, Gary P. ;
Magalhaes, Kelly Grace .
CELLS, 2020, 9 (04)
[2]   TMPRSS2, a Serine Protease Expressed in the Prostate on the Apical Surface of Luminal Epithelial Cells and Released into Semen in Prostasomes, Is Misregulated in Prostate Cancer Cells [J].
Chen, Ya-Wen ;
Lee, Ming-Shyue ;
Lucht, Amanda ;
Chou, Feng-Pai ;
Huang, Wei ;
Havighurst, Thomas C. ;
Kim, KyungMann ;
Wang, Jehng-Kang ;
Antalis, Toni M. ;
Johnson, Michael D. ;
Lin, Chen-Yong .
AMERICAN JOURNAL OF PATHOLOGY, 2010, 176 (06) :2986-2996
[3]   Androgen Receptor-Activated Enhancers Simultaneously Regulate Oncogene TMPRSS2 and lncRNA PRCAT38 in Prostate Cancer [J].
Chen, Zikai ;
Song, Xuhong ;
Li, Qidong ;
Xie, Lingzhu ;
Guo, Tangfei ;
Su, Ting ;
Tang, Chang ;
Chang, Xiaolan ;
Liang, Bin ;
Huang, Dongyang .
CELLS, 2019, 8 (08)
[4]   The Blood-Testis Barrier and Its Implications for Male Contraception [J].
Cheng, C. Yan ;
Mruk, Dolores D. .
PHARMACOLOGICAL REVIEWS, 2012, 64 (01) :16-64
[5]  
Cheng F., 2020, EFFECTS 2019 NOVEL C, DOI [10.20944/preprints202004.0280.v1, DOI 10.20944/PREPRINTS202004.0280.V1]
[6]   Collection, transport and storage procedures for blood culture specimens in adult patients: recommendations from a board of Italian experts [J].
De Plato, Francesca ;
Fontana, Carla ;
Gherardi, Giovanni ;
Privitera, Gaetano Pierpaolo ;
Puro, Vincenzo ;
Rigoli, Roberto ;
Viaggi, Bruno ;
Viale, Pierluigi .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2019, 57 (11) :1680-1689
[7]   The novel angiotensin-converting enzyme (ACE) homolog, ACE2, is selectively expressed by adult Leydig cells of the testis [J].
Douglas, GC ;
O'Bryan, MK ;
Hedger, MP ;
Lee, DKL ;
Yarski, MA ;
Smith, AI ;
Lew, RA .
ENDOCRINOLOGY, 2004, 145 (10) :4703-4711
[8]   ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Infection in COVID-19 Patients [J].
Fan, Caibin ;
Lu, Wei ;
Li, Kai ;
Ding, Yanhong ;
Wang, Jianqing .
FRONTIERS IN MEDICINE, 2021, 7
[9]   MicroRNA variants in endometriosis and its severity [J].
Farsimadan, M. ;
Ismail Haje, M. ;
Khudhur Mawlood, C. ;
Arabipour, I ;
Emamvirdizadeh, A. ;
Takamoli, S. ;
Masumi, M. ;
Vaziri, H. .
BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 2021, 78 (04) :206-210
[10]   Association analysis of KISS1 polymorphisms and haplotypes with polycystic ovary syndrome [J].
Farsimadan, M. ;
Moammadzadeh Ghosi, F. ;
Takamoli, S. ;
Vaziri, H. .
BRITISH JOURNAL OF BIOMEDICAL SCIENCE, 2021, 78 (04) :201-205
123456789