Heat Flux Analysis and Assessment of Drying Kinetics during Lyophilization of Fruits in a Pilot-Scale Freeze Dryer

被引:0
|
作者
Sedmak, Ivan [1 ]
Moze, Matic [1 ]
Kambic, Gorazd [2 ]
Golobic, Iztok [1 ]
机构
[1] Univ Ljubljana, Fac Mech Engn, Lab Thermal Technol LTT, Ljubljana 1000, Slovenia
[2] Kamb Lab Equipment, Semic 8333, Slovenia
关键词
drying kinetics; fruit drying; heat flux measurements; lyophilization; sublimation endpoint; temperature distribution;
D O I
10.3390/foods12183399
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Vacuum freeze-drying as a process for achieving high product quality has attracted increasing attention in the last decade. Particularly in the pharmaceutical field and food processing industries, lyophilization can produce high-quality products compared to samples dried by conventional methods. Despite its benefits, lyophilization is a time-consuming and costly process that requires optimization of a number of process parameters, including shelf temperature, chamber pressure, freezing rate, and process time. This paper reports on the implementation of heat flux measurements that allow noninvasive real-time determination of the endpoint of the primary drying stage as an essential parameter for the effective optimization of the overall drying time. Quantitative analysis of the drying kinetics of five fruits (kiwifruit, avocado, Asian pear, persimmon, and passion fruit) was assessed by comparing the heat flux and temperature profiles of samples during the lyophilization process. For a 24 h lyophilization cycle, average heat fluxes in the primary drying phase ranged from 250 to 570 W/m2. A significant correlation was found between the temperature and heat flux distributions at the estimated endpoint of the sublimation process and the corresponding transition into the secondary drying stage. Furthermore, good agreement was also found for the freezing phase. The use of real-time heat flux measurements proved to be a cost-effective experimental method to better understand the process variables in order to reduce the lyophilization cycle time and overall energy consumption.
引用
收藏
页数:13
相关论文
共 8 条
  • [1] Drying kinetics analysis of elephant foot yam and drying using heat pipe based solar dryer
    Pawan V. Chilbule
    Lalit P. Dhole
    Ganesh R. Chavhan
    Transactions of the Indian National Academy of Engineering, 2025, 10 (1) : 129 - 154
  • [2] Impact of Microscale and Pilot-Scale Freeze-Drying on Protein Secondary Structures: Sucrose Formulations of Lysozyme and Catalase
    Peters, Bjorn-Hendrik
    Leskinen, Jari T. T.
    Molnar, Ferdinand
    Ketolainen, Jarkko
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2015, 104 (11) : 3710 - 3721
  • [3] Investigation of drying stresses on proteins during lyophilization: Differentiation between primary and secondary-drying stresses on lactate dehydrogenase using a humidity controlled mini freeze-dryer
    Luthra, Sumit
    Obert, Jean-Philippe
    Kalonia, Devendra S.
    Pikal, Michael J.
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2007, 96 (01) : 61 - 70
  • [4] Impact of critical process and formulation parameters affecting in-process stability of lactate dehydrogenase during the secondary drying stage of lyophilization: A mini freeze dryer study
    Luthra, Sumit
    Obert, Jean-Philippe
    Kalcinia, Devendra S.
    Pikal, Michael J.
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2007, 96 (09) : 2242 - 2250
  • [5] Drying kinetics and thermo-economic analysis of drying hot water blanched ginger rhizomes in a hybrid composite solar dryer with heat exchanger
    Ndukwu, Macmanus Chinenye
    Ben Augustine, Edet
    Ugwu, Elijah
    Ibeh, Mathew Imagwuike
    Ekop, Inemesit
    Akpan, Godwin
    Udo, Anietie Effiong
    Ihediwa, Victor E.
    Akuwueke, Leonard
    Mbanasor, Jude
    Abam, Fidelis
    HELIYON, 2023, 9 (02)
  • [6] Newly designed superheated steam dryer bearing heat recovery unit: Analysis of energy efficiency and kinetics of Kelp drying
    Jia, Zhen
    Liu, Binxiong
    Li, Changcheng
    Fang, Ting
    Chen, Jinquan
    DRYING TECHNOLOGY, 2018, 36 (13) : 1619 - 1630
  • [7] Heat Transfer During Freeze-Drying Using a High-throughput vial System in view of Process Scale-up to Serum vials
    Buceta, Juan Patricio
    Trelea, Ioan Cristian
    Scutella, Bernadette
    Bourles, Erwan
    Fonseca, Fernanda
    Passot, Stephanie
    JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 110 (03) : 1323 - 1336
  • [8] Drying kinetics (mathematical modeling) and quality evaluation of herbal leaves (Adulsa and Durva) dried in small-scale greenhouse solar dryer (GHSD): Experimental investigation and comparative analysis
    Dhande, Amol
    Agarwal, Madhu
    Agarwal, Ghanshyam Das
    JOURNAL OF FOOD PROCESS ENGINEERING, 2024, 47 (08)