Survey of blood collection and transfusion practices among institutions in Africa

被引:5
作者
Jacobs, Jeremy W. [1 ]
Stephens, Laura D. [2 ]
Milner, Danny A. [3 ,4 ]
Bloch, Evan M. [5 ]
Goel, Ruchika [5 ,6 ,7 ]
Tobian, Aaron A. R. [5 ]
Shibemba, Aaron Lunda [8 ]
Eichbaum, Quentin [9 ,10 ]
机构
[1] Yale Sch Med, Dept Lab Med, New Haven, CT USA
[2] Univ Calif San Diego, Dept Pathol, La Jolla, CA USA
[3] Amer Soc Clin Patholol, Chicago, IL USA
[4] Harvard TH Chan Sch Publ Hlth, Boston, MA USA
[5] Johns Hopkins Univ, Dept Pathol, Sch Med, Baltimore, MD USA
[6] Simmons Canc Inst, SIU Sch Med, Dept Internal Med, Springfield, IL USA
[7] Simmons Canc Inst, SIU Sch Med, Dept Pediat, Springfield, IL USA
[8] Univ Teaching Hosp, Dept Pathol & Microbiol, Lusaka, Zambia
[9] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN USA
[10] Vanderbilt Univ, Sch Med, Nashville, TN USA
关键词
Africa; blood products; blood transfusion; blood typing; infectious disease; transfusion medicine; virus testing; SUB-SAHARAN AFRICA; RAPID DIAGNOSTIC-TESTS; SAFETY; CHALLENGES; REDUCTION; COUNTRIES; HIV;
D O I
10.1111/trf.17501
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction: Dramatic improvements in blood transfusion have occurred during the last two decades. Transfusion medicine services and practices in Africa remain underexplored.Methods: A survey of blood bank/transfusion medicine (BBTM) practices, available blood products, blood product source(s), pre-transfusion testing, and blood donor infectious disease testing methodologies across Africa was performed using the American Society for Clinical Pathology (ASCP) listserv. Survey recipients included hospital-based laboratories/blood banks, national transfusion medicine services, and free-standing laboratories (collectively referred to as institutions).Results: Responses from a total of 81 institutions across 22 countries were analyzed. All 81 institutions provide at least one type of blood product-whole blood, red blood cells (RBCs), platelets, plasma, and cryoprecipitate, with whole blood (90.1%, 73 of 81) and RBCs (79.0%, 64 of 81) most common, while cryoprecipitate is least common (12.4%, 10 of 81). Only five countries had a responding institution that provides all types of products. Among institutions that collect blood onsite, the most common sources of blood products are patients' family members (94.1%, 48 of 51) and pre-screened on-demand volunteer donors (82.4%, 42 of 51). The most commonly screened infectious agents are HIV and hepatitis B virus (both 81.5%), while 70.4% (57 of 81) test for hepatitis C virus (HCV) and Treponema pallidum.Discussion: This study highlights significant variability and restrictions in blood product availability, pre-transfusion testing, and blood donor infectious disease testing across Africa. Further studies are needed to ascertain barriers to improving blood donor availability, blood product safety, and infectious disease testing.
引用
收藏
页码:1849 / 1858
页数:10
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