Aging under endocrine hormone regulation

被引:9
|
作者
Xing, Yutong [1 ]
Xuan, Fan [1 ]
Wang, Kaixi [1 ]
Zhang, Huifeng [1 ]
机构
[1] Hebei Med Univ, Hosp 2, Shijiazhuang, Peoples R China
来源
FRONTIERS IN ENDOCRINOLOGY | 2023年 / 14卷
基金
英国科研创新办公室;
关键词
aging; endocrine; growth hormone; thyroid hormone; estrogen; AMES DWARF MICE; GROWTH-HORMONE; THYROID-FUNCTION; LIFE-SPAN; MENOPAUSAL TRANSITION; POSTMENOPAUSAL WOMEN; LONGITUDINAL CHANGES; SYNAPTIC PLASTICITY; FAMILIAL LONGEVITY; PREFRONTAL CORTEX;
D O I
10.3389/fendo.2023.1223529
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aging is a biological process in which the environment interacts with the body to cause a progressive decline in effective physiological function. Aging in the human body can lead to a dysfunction of the vital organ systems, resulting in the onset of age-related diseases, such as neurodegenerative and cardiovascular diseases, which can seriously affect an individual's quality of life. The endocrine system acts on specific targets through hormones and related major functional factors in its pathways, which play biological roles in coordinating cellular interactions, metabolism, growth, and aging. Aging is the result of a combination of many pathological, physiological, and psychological processes, among which the endocrine system can achieve a bidirectional effect on the aging process by regulating the hormone levels in the body. In this paper, we explored the mechanisms of growth hormone, thyroid hormone, and estrogen in the aging process to provide a reference for the exploration of endocrine mechanisms related to aging.
引用
收藏
页数:13
相关论文
共 50 条
  • [1] The endocrine regulation of aging in Caenorhabditis elegans
    Kleemann, G. A.
    Murphy, C. T.
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2009, 299 (01) : 51 - 57
  • [2] Aging and age-related diseases - From endocrine therapy to target therapy
    Bao, Qi
    Pan, Jie
    Qi, Hangfei
    Wang, Lu
    Qian, Huan
    Jiang, Fangzhen
    Shao, Zheren
    Xu, Fengzhi
    Tao, Zhiping
    Ma, Qi
    Nelson, Peter
    Hu, Xueqing
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2014, 394 (1-2) : 115 - 118
  • [3] The aging of the endocrine hypothalamus and its dependent endocrine glands
    Batrinos, Menelaos L.
    HORMONES-INTERNATIONAL JOURNAL OF ENDOCRINOLOGY AND METABOLISM, 2012, 11 (03): : 241 - 253
  • [4] Growth hormone and aging
    Bartke, A
    ENDOCRINE, 1998, 8 (02) : 103 - 108
  • [5] Growth hormone and aging
    Andrzej Bartke
    Endocrine, 1998, 8 : 103 - 108
  • [6] Growth hormone and aging
    Bartke, Andrzej
    REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2021, 22 (01) : 71 - 80
  • [7] Growth hormone, insulin and aging: The benefits of endocrine defects
    Bartke, Andrzej
    EXPERIMENTAL GERONTOLOGY, 2011, 46 (2-3) : 108 - 111
  • [8] Endocrine regulation of the growth plate
    Nilsson, O
    Marino, R
    De Luca, F
    Phillip, M
    Baron, J
    HORMONE RESEARCH, 2005, 64 (04) : 157 - 165
  • [9] The Timing Sequence and Mechanism of Aging in Endocrine Organs
    Yang, He
    Fang, Bing
    Wang, Zixu
    Chen, Yaoxing
    Dong, Yulan
    CELLS, 2023, 12 (07)
  • [10] Endocrine regulation of aging and reproduction in Drosophila
    Toivonen, Janne M.
    Partridge, Linda
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2009, 299 (01) : 39 - 50