A rare presentation of a spinal diffuse midline glioma in a child: a case report

被引:0
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作者
Isfaoun, Zineb [1 ]
Laasri, Khadija [2 ]
Jidal, Manal [2 ]
Cherradi, Nadia [3 ]
Melhaoui, Adil [4 ]
Chat, Latifa [2 ]
El Haddad, Siham [2 ]
El Kababri, Maria [1 ]
El Khorassani, Mohamed [1 ]
Kili, Amina [1 ]
El Ansari, Naoual [1 ]
Hessissen, Laila [1 ]
机构
[1] Mohammed V Univ, Childrens Hosp Rabat, Pediat Hematol & Oncol Dept, Rabat, Morocco
[2] Mohammed V Univ, Childrens Hosp Rabat, Radiol Dept, Rabat, Morocco
[3] Mohammed V Univ, Childrens Hosp Rabat, Pathol Dept, Rabat, Morocco
[4] Mohammed V Univ, Childrens Hosp Rabat, Neurosurg Dept, Rabat, Morocco
关键词
IMAGING CHARACTERISTICS;
D O I
10.11604/pamj.2023.44.183.39885
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Our patient had an extremely rare type of pediatric Diffuse Midline Glioma (DMG) with modified H3 K27 that occurred in the cervical spinal cord. Due to its location in the spinal cord, slow clinical presentation with torticollis for 7 months, and the non-specific radiological appearance of this tumour, it was initially considered to be a low-grade glioma. Based on imaging findings, the neurosurgery team performed a complete surgical resection, but the pathological features were consistent with a high-grade, diffuse midline glioma. Therefore, we are reporting a case of an altered high-grade DMG H3K27 glioma, which is difficult to diagnose due to its slow clinical symptoms which caused a delay in diagnosis, non-specific imaging, and with difficulty in accessing histopathological markers in low and middle income countries (LMIC).
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页数:7
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