A phase I study of binimetinib, a MEK inhibitor, in combination with pembrolizumab in patients with advanced non-small cell lung cancer (NSCLC)

被引：1
|
作者：
Theriau, Christopher F.
Feng, Jamie
Eng, Lawson
Shepherd, Frances A.
DeCarolis, Mary
Glenns, Vivian
Kulkarni, Swati
VanderMeer, Rachel
Zurawska-Fortin, Urszula
Hao, Desiree
Le, Lisa
Wozniczka, Isabel
Al-Kindy, Aida
Xie, Danny
Zhang, Tong
Subramanian, Vasanth
Stockley, Tracy
Bradbury, Penelope A.
Liu, Geoffrey
Leighl, Natasha B.
机构：
来源：
CANCER RESEARCH | 2023年 / 83卷 / 08期
关键词：
D O I：
10.1158/1538-7445.AM2023-CT206
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
CT206
引用
收藏
页数：3
相关论文
共 50 条
  • [41] Advanced non-small cell lung cancer - treatment with Pembrolizumab
    Silvinato, Antonio
    Floriano, Idevaldo
    Bernardo, Wanderley Marques
    REVISTA DA ASSOCIACAO MEDICA BRASILEIRA, 2020, 66 (03): : 256 - 256
  • [42] The proteasome inhibitor bortezomib in combination with gemcitabine and carboplatin in advanced non-small cell lung cancer: A california cancer consortium phase I study
    Davies, Angela M.
    Ruel, Christopher
    Lara, Primo N.
    Lau, Derick H.
    Gumerlock, Paul H.
    Bold, Richard
    Shibata, Stephen
    Lenz, Heinz-Josef
    Schenkein, David P.
    Gandara, Anddavid R.
    JOURNAL OF THORACIC ONCOLOGY, 2008, 3 (01) : 68 - 74
  • [43] A phase I study of ADXS-503 alone and in combination with pembrolizumab in subjects with metastatic squamous or non-squamous non-small cell lung cancer (NSCLC).
    Ramalingam, Suresh S.
    Stinchcombe, Tom
    Gerstner, Gregory James
    Haigentz, Missak
    Vangala, Surya
    Parsi, Megan
    Heyburn, John W.
    Kabala, Victor
    Prasad, Tuhina
    Gutierrez, Andres A.
    Goldman, Jonathan Wade
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [44] A phase I/II study of pembrolizumab (P) with gemcitabine (G) in patients (Pts) with previously-treated advanced non-small cell lung cancer (NSCLC): Phase I safety results
    Sanborn, Rachel E.
    Duffy, Regan M.
    Fisher, Brenda K.
    Perlewitz, Kelly Shea
    Redmond, William L.
    Koguchi, Yoshinobu
    Fox, Bernard A.
    JOURNAL OF CLINICAL ONCOLOGY, 2017, 35
  • [45] Vinflunine (VFL) in combination with carboplatin (CBDCA) for treatment of advanced non-small cell lung cancer (NSCLC) in chemonaive patients (pts): Phase I and pharmacokinetic study
    Robinet, G
    Afenjar, K
    Gouva, S
    Planchard, D
    Zorza, G
    Tourani, J
    LUNG CANCER, 2005, 49 : S267 - S267
  • [46] Phase I/II study of atrasentan (A) in combination with carboplatin (C) and paclitaxel (P) in chemonaive patients (pts) with advanced non-small cell lung cancer (NSCLC).
    Chiappori, A
    Haura, E
    Williams, C
    Simon, G
    Antonia, S
    Cantor, A
    Burton, MK
    Lush, R
    Sullivan, DM
    Bepler, G
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 646S - 646S
  • [47] A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer
    Michael A Morse
    Jennifer Garst
    Takuya Osada
    Shubi Khan
    Amy Hobeika
    Timothy M Clay
    Nancy Valente
    Revati Shreeniwas
    Mary Ann Sutton
    Alain Delcayre
    Di-Hwei Hsu
    Jean-Bernard Le Pecq
    H Kim Lyerly
    Journal of Translational Medicine, 3
  • [48] Phase I and pharmacokinetic study of the combination of vinflunine (VFL) and gemcitabine (GEM) for treatment of advanced non-small cell lung cancer (NSCLC) in chemonaive patients (pts)
    Bennouna, J
    Lemarie, E
    Grossi, F
    Carballido, F
    Sennelart, H
    Leger, F
    Douillard, J
    LUNG CANCER, 2005, 49 : S236 - S236
  • [49] Phase I and pharmacokinetic study of docetaxel (D), irinotecan (I), and celecoxib (C) in patients with advanced non-small cell lung cancer (NSCLC).
    Kut, V
    Avram, M
    Luong, L
    Argiris, A
    JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) : 694S - 694S
  • [50] Biomarker based phase I study of Apricoxib, a potent COX-2 inhibitor in combination with erlotinib in non-small cell lung cancer (NSCLC) patients
    Reckamp, Karen
    Patel, Ravi
    Gitlitz, Barbara
    Chen, Lin
    Jezior, Deborah
    Zaknoen, Sara
    CANCER RESEARCH, 2009, 69
12345