Two new anti-inflammatory compounds from the roots and rhizomes of Clematis terniflora var. manshurica (Rupr.) Ohwi

被引：1

作者：

Shao, Ping ^{[1
,2
]}

Dong, Sheng ^{[1
]}

Mu, Lin-Tong ^{[1
]}

Han, Ling ^{[2
]}

Lv, Chong-Ning ^{[1
]}

Yuan, Jiu-Zhi ^{[1
]}

Lu, Jin-Cai ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Materia Med, Dept Pharmaceut Bot & Authenticat TCM, Shenyang, Peoples R China

[2] NERC Pharmaceut Tradit Chinese Med, Res & Dev Ctr, Benxi, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2024年 / 38卷 / 11期

关键词：

Clematis terniflora var. manshurica (Rupr) Ohwi; chemical composition; anti-inflammatory activity; TRITERPENE SAPONINS; LIGNANS;

D O I：

10.1080/14786419.2023.2227912

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new compounds named mandshurica A (1) and mandshurica B (2), together with four known lignans (3-6) were isolated from the roots and rhizomes of Clematis terniflora var. manshurica (Rupr.) Ohwi. The structures of the new compounds were elucidated by HR-ESI-MS, 1D and 2D NMR spectroscopy. Moreover, the anti-inflammatory activity of compounds 1 and 2 were evaluated against lipopolysaccharide-induced mouse macrophage RAW264.7 cells. Compounds 1 and 2 displayed significant inhibitory effect on NO production, and compound 2 exhibited obvious inhibition on the pro-inflammatory cytokines TNF-& alpha;. Both new compounds showed potential anti-inflammatory activity.

引用

页码：1874 / 1881

页数：8

共 50 条

[31] Antioxidant and Anti-Inflammatory Constituents from Myristica elliptica var. simiarum
Chin, Chih-Hui
Chen, Zih-Rong
Chang, Tsung-Hsien
Liaw, Chia-Ching
Sung, Ping-Jyun
Cheng, Ming-Jen
Huang, Chien-Ming
Chen, Jih-Jung
CHEMISTRY OF NATURAL COMPOUNDS, 2025, 61 (01) : 27 - 31
[32] New Phenanthrenoid Dimer Derivative and Anti-Inflammatory Constituents from Juncus effusus var. decipiens
Chen, Li-Chai
Huang, Chien-Ming
Chu, Yi-Cheng
Hsieh, Yu-Hui
Cheng, Ming-Jen
Hsiao, Jen-Wen
Chen, Jih-Jung
CHEMISTRY OF NATURAL COMPOUNDS, 2024, 60 (03) : 398 - 402
[33] Production of anti-inflammatory compounds in calli and cells in suspension of Tilia americana var. mexicana
Pilar Nicasio-Torres
Alejandro Zamilpa
Manasés González-Cortazar
Maribel Herrera-Ruiz
Acta Physiologiae Plantarum, 2022, 44
[34] Antioxidant and Anti-inflammatory Compounds in the Popular Landscape Plant Berberis thunbergii var. atropurpurea
Zhang, Chuan-Rui
Schutzki, Robert E.
Nair, Muraleedharan G.
NATURAL PRODUCT COMMUNICATIONS, 2013, 8 (02) : 165 - 168
[35] Production of anti-inflammatory compounds in calli and cells in suspension of Tilia americana var. mexicana
Nicasio-Torres, Pilar
Zamilpa, Alejandro
Gonzalez-Cortazar, Manases
Herrera-Ruiz, Maribel
ACTA PHYSIOLOGIAE PLANTARUM, 2022, 44 (06)
[36] Two new compounds with anti-inflammatory activity from Alangium chinense
Yue, Yue-Dong
Xiang, Zhi-Nan
Chen, Jia-Chun
NATURAL PRODUCT RESEARCH, 2022, 36 (04) : 891 - 895
[37] Two New Compounds from Wedelia chinensis and Their Anti-inflammatory Activities
Zhong, Yuan-Lin
Zhang, Yu-Bo
Luo, Ding
Niu, Qian-Wen
Qin, Juan
He, Li-Jun
Li, Yao-Lan
Wang, Guo-Cai
CHEMISTRYSELECT, 2018, 3 (12): : 3459 - 3462
[38] Two New Homo-aro-cholestane Glycosides and a New Cholestane Glycoside from the Roots and Rhizomes of Paris polyphylla var. pseudothibetica
Xiao, Cao-Mao
Huang, Jing
Zhong, Xue-Mei
Tan, Xiao-Yan
Deng, Peng-Chi
HELVETICA CHIMICA ACTA, 2009, 92 (12) : 2587 - 2595
[39] Steroidal Sapogenins and Glycosides from the Fibrous Roots of Ophiopogon japonicas and Liriope spicata var. prolifera with Anti-inflammatory Activity
Qi, Jin
Hu, Zheng-fang
Zhou, Yi-feng
Hu, Yuan-jia
Yu, Bo-yang
CHEMICAL & PHARMACEUTICAL BULLETIN, 2015, 63 (03) : 187 - 194
[40] Chemometrics-Assisted Identification of Anti-Inflammatory Compounds from the Green Alga Klebsormidium flaccidum var. zivo
Qiu, Shi
Khan, Shabana, I
Wang, Mei
Zhao, Jianping
Ren, Siyu
Khan, Ikhlas A.
Steffek, Amy
Pfund, William P.
Li, Xing-Cong
MOLECULES, 2020, 25 (05):

← 1 2 3 4 5 →