Stearic Acid Treatment Enhancing Corrosion Resistance of Biomimetic-Deposited Calcium Phosphate Dihydrate Coating on Medical Degradable Magnesium Alloy

被引：4
作者：
Wang, Tianxiao [1 ]
Dong, Yunqian [1 ]
Xu, Yingchao [1 ]
Qu, Xingyuan [2 ]
Li, Guangyu [1 ]
Guo, Yunting [3 ,4 ]
Lian, Jianshe [1 ]
Zhang, Zhihui [3 ,4 ]
Ren, Luquan [3 ,4 ]
机构：
[1] Jilin Univ, Coll Mat Sci & Engn, Key Lab Automobile Mat, Minist Educ, Changchun 130025, Peoples R China
[2] Jilin Univ, Hosp Stomatol, Dept Periodontol, Changchun 130012, Peoples R China
[3] Jilin Univ, Key Lab Bion Engn, Minist Educ, Changchun 130025, Peoples R China
[4] Jilin Univ, Weihai Inst Bion, Weihai 264402, Peoples R China
来源：
ACS BIOMATERIALS SCIENCE & ENGINEERING | 2023年 / 9卷 / 06期
基金：
中国国家自然科学基金;
关键词：
magnesium alloy; calcium phosphate; stearicacid; corrosion resistance; biocompatibility; SILANE COUPLING AGENT; SURFACE MODIFICATION; CELL-ADHESION; HYDROXYAPATITE; BIOMATERIALS; FABRICATION; BEHAVIOR; APATITE; GROWTH; MG;
D O I：
10.1021/acsbiomaterials.3c00003
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Magnesium (Mg) alloys, a degradable material, have beenstudied for medical applications due to their excellent mechanicaland chemical properties. However, their applications are limited byrapid corrosion. In this work, stearic acid and sodiumstearate were used to treat the silane-induced calcium phosphate dihydratecoating to improve its protection for the Mg alloy further withoutchanging the bone-like structure of calcium phosphate. The differenteffects of stearic acid treatment and sodium stearate treatment werecompared. Electrochemical test and immersion test results confirmedthat the corrosion resistance of the stearic acid-treated compositecoating was greatly enhanced with a reduced corrosion current densityby 3 orders of magnitude and hydrogen evolution reduced to 1/25 after14 days. The stearic acid-treated coating also exhibited improved in vitro biocompatibility corroborated by promoted cellviability and better cell morphology.
引用
收藏
页码：3227 / 3238
页数：12
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