Phytosynthesis of gold-198 nanoparticles for a potential therapeutic radio-photothermal agent

被引：2

作者：

Juliyanto, Sumandi ^{[1
,2
]}

Pertiwi, Ligwina Dita ^{[1
]}

Nurmanjaya, Ahid ^{[1
]}

Pujiyanto, Anung ^{[1
]}

Setiawan, Herlan ^{[1
]}

Rindiyantono, Fernanto ^{[1
]}

Abidin

Fikri, Ahsanal

Putra, Amal Rezka ^{[1
,2
]}

Forentin, Alfian Mahardika ^{[1
]}

Susilo, Veronika Yulianti ^{[1
]}

Febrian, Muhamad Basit ^{[1
]}

Ritawidya, Rien ^{[1
]}

Yulizar, Yoki ^{[1
,2
]}

机构：

[1] BRIN, Res Ctr Radioisotope Radiopharmaceut & Biodosimet, Natl Res & Innovat Agcy, Res Org Nucl Energy,Puspiptek Area, Bldg 11, South Tangerang 15314, Indonesia

[2] Univ Indonesia, Fac Math & Nat Sci, Dept Chem, Depok 16424, Indonesia

来源：

APPLIED RADIATION AND ISOTOPES | 2024年 / 204卷

关键词：

Gold-198; nanoparticles; Phytosynthesis; Characterization; Cancer cells; Radio-photothermal therapy; GOLD NANOPARTICLES; CURCUMA; SHAPES;

D O I：

10.1016/j.apradiso.2023.111141

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We produced spherical gold-198 nanoparticles with an average size of 41 nm, good stability, and high radio-chemical purity for a promising single agent of radio-photothermal therapy using Curcuma longa rhizome extract as a reducing and capping agent. The combination of in vitro treatment using gold-198 nanoparticles and irra-diation of 980 nm wavelength lasers with a power output of 2 W/cm2 induced hyperthermia temperature and exhibited enhancement of the percentage dead on MDA-MB-123 cancer cells compared to gold-198 nanoparticles alone.

引用

页数：9

共 52 条

[51] Single agent nanoparticle for radiotherapy and radio-photothermal therapy in anaplastic thyroid cancer
Zhou, Min
Chen, Yunyun
Adachi, Makoto
Wen, Xiaoxia
Erwin, Bill
Mawlawi, Osama
Lai, Stephen Y.
Li, Chun
[J]. BIOMATERIALS, 2015, 57 : 41 - 49
[52] Synthesis of 198Au nanoparticles sub 10 nm due optimization on local dose by Monte Carlo simulations for cancer treatment
Zutta Villate, Julian Mateo
Rojas, Jessika Viviana
Hahn, Marc Benjamin
Anselmo Puerta, Jorge
[J]. JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2022, 331 (07) : 3033 - 3041

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