Responses of antibiotic resistance genes in the enhanced biological phosphorus removal system under various antibiotics: Mechanisms and implications

被引：3
作者：
Wu, Ligui [1 ,2 ]
Wu, Qiaofeng [1 ,3 ]
Xu, Jingcheng [1 ]
Rong, Lingling [2 ]
Yu, Xiaoli [2 ]
Cai, Chen [1 ]
Huang, Xiangfeng [1 ]
Zou, Xiaoming [2 ]
机构：
[1] Tongji Univ, Coll Environm Sci & Engn, 28 Xueyuan Rd, Shanghai 200092, Peoples R China
[2] Jinggangshan Univ, Sch Life Sci, Jian 343009, Peoples R China
[3] Fuzhou Urban & Rural Construction Grp Co Ltd, Fuzhou 350007, Peoples R China
来源：
SCIENCE OF THE TOTAL ENVIRONMENT | 2023年 / 905卷
基金：
中国国家自然科学基金;
关键词：
Antibiotics; Antibiotic resistant genes; Enhanced biological phosphorus removal; system; Horizontal gene transfer; MICROBIAL COMMUNITY; ZNO NANOPARTICLES; ACTIVATED-SLUDGE; PERFORMANCE; REACTORS; NITROGEN; OXYTETRACYCLINE; ERYTHROMYCIN; SULFONAMIDES; BACTERIA;
D O I：
10.1016/j.scitotenv.2023.167247
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The effects of antibiotics on the proliferation of antibiotic resistant genes (ARGs) in WWTPs have drawn great attention in recent years. The effects of antibiotics on ARGs in the enhanced biological phosphorus removal (EBPR) system and its mechanisms, however, are still not well understood. In this study, EBPR systems were constructed using activated sludge to investigate the effects of ten commonly detected antibiotics in the envi-ronment on the proliferation of ARGs and the mechanisms involved. The results showed that the total abundance of ARGs increased to varying degrees with the addition of different antibiotics (0.05 mmol/L), and the top 30 ARGs increased by 271.1 % to 370.0 %. Mobile genetic elements (MGEs), functional modules, and the bacteria community were consistently related to the changes in ARGs. Refractory antibiotics, in particular, have a
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页数：11
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