Small molecules in the race of COVID-19 drug development

被引：0

作者：

Jash, Rajiv ^{[1
]}

Prasanth, D. S. N. B. K. ^{[2
]}

Jash, Moumita ^{[1
,3
]}

Suneetha, Achanti ^{[4
]}

机构：

[1] Sanaka Educ Trust Grp Inst, Dept Pharm, Durgapur 713212, W Bengal, India

[2] KVSR Siddhartha Coll Pharmaceut Sci, Dept Pharmacognosy, Vijayawada 520010, Andhra Prades, India

[3] Indian Inst Technol, Dept Biosci & Bioengn, Jodhpur 342037, Rajasthan, India

[4] KVSR Siddhartha Coll Pharmaceut Sci, Dept Pharmaceut Anal, Vijayawada 520010, Andhra Prades, India

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2023年 / 25卷 / 12期

关键词：

Remdesivir; M-Pro Inhibitors; COVID-19; Nirmatrelvir; Azvudine; RESPIRATORY SYNDROME CORONAVIRUS; REMDESIVIR; HYDROXYCHLOROQUINE; CHLOROQUINE; VIRUS; MECHANISMS; PROTEASE; CHLOROQUINE/HYDROXYCHLOROQUINE; COMBINATION; INHIBITION;

D O I：

10.1080/10286020.2023.2197595

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

COVID-19, caused by SARS-CoV-2, is spreading worldwide, regardless of different continents, increasing the death toll to almost five million, with more than 300 million reported cases. Researchers have been fighting the greatest threats to human civilization. This report provides a glimpse of ongoing small-molecule research on COVID-19 drugs to save millions of lives, which may provide researchers with a better understanding of rigorously investigated therapeutic agents. This report emphasizes the chemical structures and mechanisms of activity along with drug target information for several small molecules, including marketable drugs and agents under investigation. [GRAPHICS] .

引用

页码：1133 / 1154

页数：22

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