Association of Osteoarthritis and Functional Limitations With Cognitive Impairment Among Older Adults in the United States

被引：2

作者：

Rakutt, Maxwell J. ^{[1
]}

Mace, Ryan A. ^{[2
]}

Conley, Caitlin E. W. ^{[3
]}

Stone, Austin V. ^{[3
]}

Duncan, Stephen T. ^{[3
]}

Greenberg, Jonathan ^{[2
]}

Landy, David C. ^{[3
]}

Vranceanu, Ana-Maria ^{[2
]}

Jacobs, Cale A. ^{[4
]}

机构：

[1] Univ Kentucky, Coll Med, Lexington, KY 40506 USA

[2] Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA

[3] Univ Kentucky, Dept Orthopaed Surg & Sports Med, Lexington, KY 40506 USA

[4] Brigham & Womens Hosp, Massachusetts Gen Brigham Sports Med, 75 Francis St, Boston, MA 02115 USA

来源：

JOURNAL OF AGING AND HEALTH | 2023年 / 35卷 / 09期

关键词：

osteoarthritis; cognitive impairment; functional limitations; aging; dementia; INSTRUMENTAL ACTIVITIES; ALZHEIMERS-DISEASE; SYSTEMIC INFLAMMATION; PHYSICAL-ACTIVITY; WALKING PROGRAM; DEMENTIA RISK; DISABILITY; DECLINE; PERFORMANCE; PAIN;

D O I：

10.1177/08982643231153459

中图分类号：

R4 [临床医学]; R592 [老年病学];

学科分类号：

1002 ; 100203 ; 100602 ;

摘要：

Objective: Given overlapping pathophysiology, this study sought to assess the association between osteoarthritis (OA), functional impairment, and cognitive impairment in the aging population. Methods: The National Health and Nutrition Examination Survey was used to identify participants >60 years of age. We analyzed multivariable associations of grouped participants that underwent cognitive function testing using linear and logistic regression, adjusting for sex, age, race, and ethnicity. Results: Of 2776 identified participants representing a population of 50,242,917, 40% did not report OA or functional limitations; 21% had OA but not functional limitations; 15% did not have OA but had functional limitations; 17% had OA and related functional limitations; and 7% had OA and non-arthritic functional limitations. OA was not independently associated with cognitive impairment. Contrarily, functional limitations were associated with cognitive impairment regardless of OA diagnosis. Discussion: Cognitive impairment is not associated with OA, but rather functional limitations, potentially guiding future intervention.

引用

页码：643 / 650

页数：8