AN ECO-FRIENDLY ULTRASOUND-ASSISTED ONE-POT THREE-COMPONENT SYNTHESIS OF 1,4-DIHYDROPYRIMIDO [1,2-A]BENZIMIDAZOLE DERIVATIVES CATALYZED BY MAGHNITE-H+

被引：0

作者：

Ben Messaoud, Hadda ^{[1
]}

Benlahreche, Boumadiene ^{[1
,2
]}

Djemoui, Amar ^{[1
]}

Souli, Lahcene ^{[1
]}

Lahrech, Mokhtar Boualem ^{[1
]}

机构：

[1] Ziane Achour Univ Djelfa, Fac Exact Sci & Informat, Lab Organ Chem & Nat Subst, Djelfa, Algeria

[2] Univ Oran 1 Ahmed Ben Bella, Fac Exact & Appl Sci, Dept Chem, Lab Fine Chem, PB 1524, El Mnaouer, Algeria

来源：

HETEROCYCLIC LETTERS | 2023年 / 13卷 / 03期

关键词：

1,4-dihydropyrimido[1,2-a]benzimidazole; One-pot multicomponent reactions; Benzaldehyde; ketone; 2-Aminobenzimidazole; Maghnite-H+; Ultrasound irradiation; EFFICIENT; ACID; CLAY;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient procedure is developed for the synthesis of 1,4-dihydropyrimido[1,2a]benzimidazole derivatives (DHPBz) via one-pot multi-component reaction of an aromatic aldehydes, ketones and 2-aminobenzimidazole, with use of a proton exchanged Algerian montmorillonite clay (Maghnite-H+) as green catalyst under ultrasound irradiation. This approach has the major advantages of short reaction time, good yields, easy operation, low energy consumption, and environmental friendliness. In addition, the solid non-toxic catalyst could be removed from the reaction mixture by simple filtration and recyclable without a lack of catalytic activity. All of the products were characterized by IR and NMR spectroscopy, MS, and elemental analysis.

引用

页码：449 / 457

页数：9

共 29 条

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