Antithyroid Drug-Induced Agranulocytosis: A Case Report

被引：1

作者：

MacKay, Micaela ^{[1
]}

Clewis, Madison C. ^{[1
]}

Sweet, Patrick ^{[1
]}

机构：

[1] Univ Texas Med Branch, Internal Med, Galveston, TX 77555 USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 11期

关键词：

graves' disease; drug -induced agranulocytosis; antithyroid drugs; agranulocytosis; drug; -reaction; methimazole; HYPERTHYROIDISM;

D O I：

10.7759/cureus.48264

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Agranulocytosis is a rare but life-threatening complication of methimazole and propylthiouracil, antithyroid drugs (ATDs) prescribed for the treatment of hyperthyroidism. We report the case of a 41-year-old female who presented to our institution with complaints of fevers, chills, sore throat, myalgias, and generalized weakness one month after treatment initiation with methimazole. A complete blood count at admission revealed agranulocytosis with an absolute neutrophil count of 0/mu l. After discontinuation of the medication, she was treated with granulocyte-colony stimulating factor and intravenous broad-spectrum antibiotics, which improved her condition on day seven of hospitalization.

引用

页数：4

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