Visible-Light-Induced Intramolecular Tandem Cyclization of Unactivated Indoloalkynes for the Synthesis of Sulfonylated and Selenylated Indolo[1,2-a]quinolines

被引：4
|
作者：
Zhang, Shouren [1 ]
Yuan, Jinwei [2 ]
Huang, Guangchao [2 ]
Ma, Chengjia [2 ]
Yang, Jingjing [2 ]
Yang, Liangru [2 ]
Xiao, Yongmei [2 ]
Qu, Lingbo [3 ]
机构：
[1] Huanghe Sci & Technol Coll, Inst Nanostruct Funct Mat, Henan Key Lab Nanocomposites & Applicat, Zhengzhou 450006, Henan, Peoples R China
[2] Henan Univ Technol, Sch Chem & Chem Engn, Zhengzhou 450001, Peoples R China
[3] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Peoples R China
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 16期
关键词：
C-H ACTIVATION; PHOTOREDOX CATALYSIS; FACILE ACCESS; CASCADE; SPIROCYCLIZATION; INDOLES; ALKYNES; DERIVATIVES; INHIBITOR; SCAFFOLDS;
D O I：
10.1021/acs.joc.3c00997
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A convenient and efficient visible-light-induced methodhas beendeveloped for the construction of sulfonated and selenylated indolo[1,2-a]quinolines through sulfonyl or selenyl radical-initiatedtandem cyclization of unactivated alkynes with sodium sulfinates ordiaryl diselenides under mild conditions. This protocol, which simplyutilizes visible light as the safe and eco-friendly energy sourceand an inexpensive and nontoxic organic dye as a photocatalyst withoutthe aid of an external photocatalyst, provides various sulfonyl- andselenyl-containing indolo[1,2-a]quinolines in moderateto good yields.
引用
收藏
页码：11712 / 11727
页数：16
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