The influence of interradicular anatomy on the predictability of periodontal regenerative therapy of furcation defects: a retrospective, multicenter clinical study

被引：4

作者：

Limiroli, Enrico ^{[1
,2
]}

Calo, Andrea ^{[1
,2
]}

Cortellini, Pierpaolo

Eickholz, Peter ^{[3
]}

Katayama, Akihiko

Majzoub, Jad ^{[4
]}

Wong, Jennifer ^{[5
]}

McClain, Pamela

Cortinovis, Ivan ^{[6
]}

Rasperini, Giulio ^{[1
,2
]}

机构：

[1] Univ Milan, Dept Biomed Surg & Dent Sci, Milan, Italy

[2] Fdn IRCCS Ca Granda Polyclin, Via Commenda 10, I-20122 Milan, Italy

[3] Johann Wolfgang Goethe Univ Frankfurt Main, Ctr Dent & Oral Med Carolinum, Dept Periodontol, D-60596 Frankfurt, Germany

[4] Univ Michigan, Dept Periodont & Oral Med, Ann Arbor, MI USA

[5] Harvard Sch Dent Med, Dept Oral Med Infect & Immun, Div Periodontol, Boston, MA USA

[6] Univ Milan, Dept Clin Sci & Community Hlth, Lab GA Maccacaro, Milan, Italy

来源：

CLINICAL ORAL INVESTIGATIONS | 2023年 / 27卷 / 07期

关键词：

Furcation defect furcation treatment; Root divergence; Furcation anatomy; Regenerative therapy; Furcation regeneration; GUIDED TISSUE REGENERATION; CLASS-II; INVOLVEMENT; MOLARS; PARAMETERS; SURVIVAL;

D O I：

10.1007/s00784-023-04995-3

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

BackgroundThe relationship between the anatomy of the interradicular space and success in regenerative therapy of furcation defects is discussed in this paper. The goal of this retrospective, multicenter clinical study is to clinically evaluate the relationship between the interradicular conformation and regenerative therapy success with the use of a novel measurement method.MethodsOne hundred thirty-eight radiographs of mandibular molars with furcation defects that had been treated with regenerative therapy were collected from six clinical centers. Data on the type of therapy and clinical parameters before and after treatment (follow-up of at least 12 months) were collected. The radiographs (before surgery and at least 12 months postoperatively) were measured with a visual evaluation method by a blind operator using graphics software.ResultsSuccess, defined as a reduction in horizontal and vertical furcation involvement, decrease in probing depths, and increase in clinical attachment level, was statistically assessed on 138 regenerated molars sites and were related to clinical variables such as age, sex, center, and treatment. No correlation was found between success in regenerative therapy and the conformation of the interradicular space, measured with a visual ratio method and a standard linear measurement.At the univariate analysis, the parameters that had a correlation with success were center, extent of furcation involvement, treatment, and sex. The use of enamel matrix derivative (EMD) seemed to be the most favorable therapy, with increase in CAL gain and reduction of vertical or horizontal furcation involvement.ConclusionsThe regenerative outcome was not significantly influenced by the anatomy of furcation. The center, the degree of furcation involvement, sex, and treatment (EMD) were significantly associated with higher success of periodontal regeneration.

引用

页码：3779 / 3786

页数：8

共 31 条

[31] Patterns of Care and Clinical Outcomes of HER2-positive Metastatic Breast Cancer Patients With Newly Diagnosed Stage IV or Recurrent Disease Undergoing First-line Trastuzumab-based Therapy: A Multicenter Retrospective Cohort Study [J].

Lambertini, Matteo ;

Ferreira, Arlindo R. ;

Di Meglio, Antonio ;

Poggio, Francesca ;

Puglisi, Fabio ;

Sottotetti, Federico ;

Montemurro, Filippo ;

Poletto, Elena ;

Bernardo, Antonio ;

Risi, Emanuela ;

Dellepiane, Chiara ;

Sini, Valentina ;

Minuti, Gabriele ;

Grasso, Donatella ;

Fancelli, Sara ;

Del Mastro, Lucia .

CLINICAL BREAST CANCER, 2017, 17 (08) :601-+

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