Synovial sarcoma with intra-abdominal metastasis causing hemoperitoneum: a case-report

被引:1
作者
Thompson, Joshua J. J. [1 ]
Koch, Rachel A. A. [1 ]
Keedy, Vicki L. L. [2 ]
Magge, Deepa R. R. [1 ,2 ,3 ]
机构
[1] Vanderbilt Univ Sch Med, Dept Surg, Preston Res Bldg,2220 Pierce Ave, Nashville, TN 37232 USA
[2] Vanderbilt Univ Sch Med, Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[3] Vanderbilt Univ Sch Med, Dept Surg Oncol, Nashville, TN USA
关键词
Synovial sarcoma; Screening; Metastasis; SOFT-TISSUE SARCOMA; SSX FUSION TYPE; MULTICENTER;
D O I
10.1186/s12957-023-02885-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Synovial sarcoma is a rare soft tissue sarcoma which frequently involves the upper or lower extremities. Soft tissue sarcomas including synovial sarcoma have a propensity to metastasize to the lungs, and there are very few reports of metastatic lesions in other locations.Here, we report a case of a 49-year-old patient who underwent neoadjuvant chemoradiation for an upper extremity synovial sarcoma and presented approximately 4 years later with abdominal pain and hemoperitoneum and was ultimately found to have metastatic synovial sarcoma involving the greater curvature of the stomach and surrounding peri-gastric soft tissue. We describe the multidisciplinary management of this complex patient presentation and propose that expanded surveillance imaging beyond that of the local tumor resection bed and the chest may be beneficial especially in tumors with high-risk features.
引用
收藏
页数:6
相关论文
共 14 条
  • [1] The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma
    Cironi, Luisa
    Petricevic, Tanja
    Vieira, Victor Fernandes
    Provero, Paolo
    Fusco, Carlo
    Cornaz, Sandrine
    Fregni, Giulia
    Letovanec, Igor
    Aguet, Michel
    Stamenkovic, Ivan
    [J]. SCIENTIFIC REPORTS, 2016, 6
  • [2] Synovial Sarcoma of the Extremities: A Literature Review
    Faur, Cosmin Ioan
    Pop, Daniel Laurentiu
    Abu Awwad, Ahmed
    Zamfir, Carmen Lacramioara
    Folescu, Roxana
    Gurgus, Daniela
    Motoc, Andrei Gheorghe Marius
    Patrascu, Jenel Marian
    Motoi, Sorin Bogdan
    Belei, Oana
    Ungureanu, Ana Maria
    [J]. APPLIED SCIENCES-BASEL, 2021, 11 (16):
  • [3] Synovial sarcoma in children and adolescents: the European Pediatric Soft Tissue Sarcoma Study Group prospective trial (EpSSG NRSTS 2005)
    Ferrari, A.
    De Salvo, G. L.
    Brennan, B.
    van Noesel, M. M.
    De Paoli, A.
    Casanova, M.
    Francotte, N.
    Kelsey, A.
    Alaggio, R.
    Oberlin, O.
    Carli, M.
    Ben-Arush, M.
    Bergeron, C.
    Merks, J. H. M.
    Jenney, M.
    Stevens, M. C.
    Bisogno, G.
    Orbach, D.
    [J]. ANNALS OF ONCOLOGY, 2015, 26 (03) : 567 - 572
  • [4] Soft Tissue Sarcoma Across the Age Spectrum: A Population-Based Study From the Surveillance Epidemiology and End Results Database
    Ferrari, Andrea
    Sultan, Iyad
    Huang, Tseng Tien
    Rodriguez-Galindo, Carlos
    Shehadeh, Ahmad
    Meazza, Cristina
    Ness, Kirsten K.
    Casanova, Michela
    Spunt, Sheri L.
    [J]. PEDIATRIC BLOOD & CANCER, 2011, 57 (06) : 943 - 949
  • [5] Greenberg David D., 2016, Sarcoma, V2016, P8289509, DOI 10.1155/2016/8289509
  • [6] Histologic grade, but not SYT-SSX fusion type, is an important prognostic factor in patients with synovial sarcoma: A multicenter, retrospective analysis
    Guillou, L
    Benhattar, L
    Bonichon, F
    Gallagher, G
    Terrier, P
    Stauffer, E
    Somerhausen, NDA
    Michels, JJ
    Jundt, G
    Vince, DR
    Taylor, S
    Genevay, M
    Collin, F
    Trassard, M
    Coindre, JM
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (20) : 4040 - 4050
  • [7] Treatment of limb synovial sarcoma with metastasis at presentation
    Guo, Pan
    Zhao, Renbo
    Zhou, Yuanxi
    Shen, Yuxin
    [J]. MEDICINE, 2020, 99 (23)
  • [8] SS18-SSX2 and the mitochondrial apoptosis pathway in mouse and human synovial sarcomas
    Jones, K. B.
    Su, L.
    Jin, H.
    Lenz, C.
    Randall, R. L.
    Underhill, T. M.
    Nielsen, T. O.
    Sharma, S.
    Capecchi, M. R.
    [J]. ONCOGENE, 2013, 32 (18) : 2365 - 2371
  • [9] Joseph N, 2019, J CLIN ONCOL, V37
  • [10] Synovial sarcomas usually metastasize after >5 years: a multicenter retrospective analysis with minimum follow-up of 10 years for survivors
    Krieg, A. H.
    Hefti, F.
    Speth, B. M.
    Jundt, G.
    Guillou, L.
    Exner, U. G.
    von Hochstetter, A. R.
    Cserhati, M. D.
    Fuchs, B.
    Mouhsine, E.
    Kaelin, A.
    Klenke, F. M.
    Siebenrock, K. A.
    [J]. ANNALS OF ONCOLOGY, 2011, 22 (02) : 458 - 467