Severity and intractableness of skin infections caused by Panton-Valentine leukocidin-positive methicillin-resistant Staphylococcus aureus

被引：0

作者：

Kawakami, Tamihiro ^{[1
]}

Yokoyama, Kae ^{[1
]}

Ikeda, Takaharu ^{[1
]}

Kaneko, Hiroshi ^{[2
]}

Watanabe, Yuji ^{[3
]}

Nakaminami, Hidemasa ^{[2
]}

机构：

[1] Tohoku Med & Pharmaceut Univ, Div Dermatol, 1-15-1 Fukumuro,Miyagino Ku, Sendai, Miyagi 9838536, Japan

[2] Tokyo Univ Pharm & Life Sci, Sch Pharm, Dept Clin Microbiol, Tokyo, Japan

[3] Tohoku Med & Pharmaceut Univ Hosp, Div Clin Lab, Sendai, Japan

来源：

JOURNAL OF CUTANEOUS IMMUNOLOGY AND ALLERGY | 2023年 / 6卷 / 03期

关键词：

methicillin-resistant Staphylococcus aureus; Panton-Valentine leukocidin; USA300;

D O I：

10.1002/cia2.12294

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Cases of skin infections caused by Panton-Valentine leukocidin (PVL)-positive methicillin-resistant Staphylococcus aureus (MRSA), particularly USA300 clone, have been increasing in Japan. We report that clinical findings of 5 patients with PVL-positive MRSA and compared to those of four patients with PVL-negative MRSA. Severities of patients with PVL-positive MRSA were significantly higher than those of patients with PVL-negative MRSA. Average durations of antimicrobial therapy for patients with PVL-positive MRSA were 3.4-fold longer than those for patients with PVL-negative MRSA. Our data suggest that PVL-positive MRSA should be deal with a causative agent for intractable skin infections in Japan likewise other countries.

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收藏

页码：94 / 97

页数：4

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