ESGO-ESMO-ESP consensus conference recommendations on ovarian cancer: pathology and molecular biology and early, advanced and recurrent disease

被引：116

作者：

Ledermann, J. A. ^{[1
]}

Matias-Guiu, X. ^{[2
,3
,4
]}

Amant, F. ^{[5
,6
]}

Concin, N. ^{[7
,8
]}

Davidson, B. ^{[9
,10
]}

Fotopoulou, C. ^{[11
]}

Gonzalez-Martin, A. ^{[12
,13
]}

Gourley, C. ^{[14
]}

Leary, A. ^{[15
]}

Lorusso, D. ^{[16
,17
]}

Banerjee, S. ^{[18
,19
]}

Chiva, L. ^{[20
]}

Cibula, D. ^{[21
,22
]}

Colombo, N. ^{[23
,24
]}

Croce, S. ^{[25
]}

Eriksson, A. G. ^{[10
,26
]}

Falandry, C. ^{[27
,28
]}

Fischerova, D. ^{[21
,22
]}

Harter, P. ^{[8
,29
]}

Joly, F. ^{[30
]}

Lazaro, C. ^{[31
]}

Lok, C. ^{[6
]}

Mahner, S. ^{[29
,32
]}

Marme, F. ^{[29
,33
,34
]}

Marth, C. ^{[7
]}

McCluggage, W. G. ^{[35
]}

Mcneish, I. A. ^{[11
]}

Morice, P. ^{[36
]}

Nicum, S. ^{[1
]}

Oaknin, A. ^{[37
]}

Perez-Fidalgo, J. A. ^{[38
]}

Pignata, S. ^{[39
]}

Ramirez, P. T. ^{[40
]}

Ray-Coquard, I. ^{[41
]}

Romero, I. ^{[42
]}

Scambia, G. ^{[16
,17
]}

Sehouli, J. ^{[43
,44
]}

Shapira-Frommer, R. ^{[45
]}

Sundar, S. ^{[46
,47
]}

Tan, D. S. P. ^{[48
,49
,50
,51
]}

Taskiran, C. ^{[38
]}

van Driel, W. J. ^{[40
]}

Vergote, I. ^{[52
]}

Planchamp, F. ^{[37
]}

Sessa, C. ^{[48
,49
,50
,51
]}

Fagotti, A. ^{[6
]}

机构：

[1] UCL, UCL Canc Inst, Dept Oncol, London, England

[2] CIBERONC, Madrid, Spain

[3] Univ Lleida, Hosp Univ Arnau Vilanova, Dept Pathol, IRBLLEIDA, Lleida, Spain

[4] Univ Barcelona, Hosp Univ Bellvitge, Dept Pathol, IDIBELL, Barcelona, Spain

[5] Univ Hosp Leuven, Leuven Canc Inst, Dept Gynaecol Oncol, Leuven, Belgium

[6] Netherlands Canc Inst, Ctr Gynecol Oncol Amsterdam, Dept Gynecol, Amsterdam, Netherlands

[7] Med Univ Innsbruck, Dept Obstet & Gynaecol, Innsbruck, Austria

[8] Evang Kliniken Essen Mitte, Dept Gynaecol & Gynaecol Oncol, Essen, Germany

[9] Oslo Univ Hosp, Norwegian Radium Hosp, Dept Pathol, Oslo, Norway

[10] Univ Oslo, Inst Clin Med, Fac Med, Oslo, Norway

[11] Imperial Coll London, Fac Med, Dept Surg & Canc, London, England

[12] Clin Univ Navarra, Canc Ctr, Dept Med Oncol, Madrid, Spain

[13] Clin Univ Navarra, Canc Ctr, Program Solid Tumours Cima, Madrid, Spain

[14] Univ Edinburgh, Inst Genet & Canc, Canc Res UK Scotland Ctr, Edinburgh, Midlothian, Scotland

[15] Inst Gustave Roussy, Dept Med, Villejuif, France

[16] Fdn Policlin Univ A Gemelli IRCCS, Div Gynecol Oncol, Rome, Italy

[17] Univ Cattolica Sacro Cuore, Dept Woman Child & Publ Hlth, Rome, Italy

[18] Royal Marsden NHS Fdn Trust, London, England

[19] Inst Canc Res, London, England

[20] Clin Univ Navarra, Dept Gynaecol & Obstet, Canc Ctr, Navarra, Spain

[21] Charles Univ Prague, Fac Med 1, Dept Gynecol Obstet & Neonatol, Prague, Czech Republic

[22] Gen Univ Hosp Prague, Prague, Czech Republic

[23] Ist Europeo Oncol IRCCS, Dept Gynecol Oncol, Milan, Italy

[24] Univ Milano Bicocca, Dept Med & Surg, Milan, Italy

[25] Bergonie Inst, Dept Biopathol, Bordeaux, France

[26] Oslo Univ Hosp, Norwegian Radium Hosp, Dept Gynecol Oncol, Div Canc Med, Oslo, Norway

[27] Hosp Civils Lyon, Inst Aging, Lyon, France

[28] Univ Lyon 1, CarMeN Lab, INSERM,U1060, INRAE,U1397,Hosp Civils Lyon, Pierre Benite, France

[29] Arbeitsgemeinschaft Gynakol Onkol AGO Study Grp, Ravensburg, Germany

[30] Univ Caen Normandy, Ctr Francois Baclesse, Dept Med Oncol, GINECO Grp, Caen, France

[31] CIBERONC, Hereditary Canc Program, Catalan Inst Oncol, ICO,IDIBELL, Barcelona, Spain

[32] Ludwig Maximilians Univ Munchen, Univ Hosp, Dept Obstet & Gynecol, Munich, Germany

[33] Univ Hosp Mannheim, Dept Obstet & Gynecol, Mannheim, Germany

[34] Heidelberg Univ, Med Fac Mannheim, Mannheim, Germany

[35] Belfast Hlth & Social Care Trust, Dept Pathol, Belfast, Antrim, North Ireland

[36] Gustave Roussy Canc Campus, Dept Gynecol Surg, Villejuif, France

[37] Hosp Univ Vall Hebron, Gynaecol Canc Programme, Vall Hebron Inst Oncol VHIO, Vall Hebron Barcelona Hosp Campus, Barcelona, Spain

[38] Hosp Clin Univ, Dept Med Oncol, INCLIVA, CIBERONC, Valencia, Spain

[39] IRCCS Fdn Pascale, Ist Nazl Tumori Napoli, Dept Urol & Gynecol, Naples, Italy

[40] Houston Methodist Hosp, Dept Obstet & Gynecol, Houston, TX USA

[41] Univ Claude Bernard, Ctr Leon Berard, Dept Med Oncol, Lyon, France

[42] Inst Valenciano Oncol, Dept Med Oncol, Valencia, Spain

[43] North Eastern German Soc Gynecol Oncol NOGGO, Berlin, Germany

[44] Charite Berlin Univ Med, Ctr Oncol Surg, Dept Gynecol, Berlin, Germany

[45] Sheba Med Ctr, Ramat Gan, Israel

[46] Univ Birmingham, Inst Canc & Genom Sci, Birmingham, W Midlands, England

[47] City Hosp, Pan Birmingham Gynaecol Canc Ctr, Birmingham, W Midlands, England

[48] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore

[49] Natl Univ Singapore, Natl Univ Singapore NUS Ctr Canc Res, Yong Loo Lin Sch Med, Singapore, Singapore

[50] Natl Univ Singapore, Canc Sci Inst, Singapore, Singapore

来源：

ANNALS OF ONCOLOGY | 2024年 / 35卷 / 03期

关键词：

chemotherapy; maintenance treatment; molecular biology; ovarian cancer; pathology; surgery; HYPERTHERMIC INTRAPERITONEAL CHEMOTHERAPY; TUBAL INTRAEPITHELIAL CARCINOMA; SEROUS BORDERLINE TUMORS; NEOADJUVANT CHEMOTHERAPY; CYTOREDUCTIVE SURGERY; ADJUVANT CHEMOTHERAPY; MAINTENANCE THERAPY; FALLOPIAN-TUBE; OPEN-LABEL; QUALITY INDICATORS;

D O I：

10.1016/j.annonc.2023.11.015

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The European Society of Gynaecological Oncology, the European Society for Medical Oncology (ESMO) and the European Society of Pathology held a consensus conference (CC) on ovarian cancer on 15-16 June 2022 in Valencia, Spain. The CC panel included 44 experts in the management of ovarian cancer and pathology, an ESMO scientific advisor and a methodologist. The aim was to discuss new or contentious topics and develop recommendations to improve and harmonise the management of patients with ovarian cancer. Eighteen questions were identified for discussion under four main topics: (i) pathology and molecular biology, (ii) early -stage disease and pelvic mass in pregnancy, (iii) advanced stage (including older/frail patients) and (iv) recurrent disease. The panel was divided into four working groups (WGs) to each address questions relating to one of the four topics outlined above, based on their expertise. Relevant scientific literature was reviewed in advance. Recommendations were developed by the WGs and then presented to the entire panel for further discussion and amendment before voting. This manuscript focuses on the recommendation statements that reached a consensus, their voting results and a summary of evidence supporting each recommendation.

引用

页码：248 / 266

页数：19

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