Antiphospholipid Antibodies Associated with Native Arteriovenous Fistula Complications in Hemodialysis Patients: A Comprehensive Review of the Literature

被引:6
作者
Taghavi, Maxime [1 ,2 ]
Jabrane, Abla [1 ]
Jacobs, Lucas [1 ]
Mesquita, Maria Do Carmo Filomena [1 ]
Demulder, Anne [3 ]
Nortier, Joelle [1 ,2 ]
机构
[1] Univ Libre Bruxelles ULB, Brugmann Univ Hosp, Nephrol & Dialysis Dept, B-1020 Brussels, Belgium
[2] Univ Libre Bruxelles ULB, Fac Med, Lab Expt Nephrol, B-1070 Brussels, Belgium
[3] Univ Libre Bruxelles ULB, Brugmann Univ Hosp, Lab Hematol & Haemostasis LHUB ULB, B-1020 Brussels, Belgium
关键词
antiphospholipid antibodies; antiphospholipid syndrome; arteriovenous fistula; hemodialysis; thrombosis; stenosis; maturation failure; CHRONIC KIDNEY-DISEASE; VASCULAR ACCESS THROMBOSIS; ANTICARDIOLIPIN ANTIBODIES; MAINTENANCE HEMODIALYSIS; LUPUS ANTICOAGULANT; ENDOTHELIAL-CELLS; RISK-FACTORS; THROMBOPHILIA; OCCLUSION; HYPERPLASIA;
D O I
10.3390/antib13010001
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Antiphospholipid antibody (aPL)-persistent positivity is frequent in hemodialysis (HD) patients. Native arteriovenous fistula (AVF) complications such as stenosis and thrombosis are among the most important causes of morbidity and mortality in hemodialysis patients. The association between aPL positivity and AVF thrombosis seems to now be well established. However, whether aPL positivity is associated with other AVF complications, such as maturation failure or stenosis, is not well known. Given the significant impact of AVF failure on patient's prognosis, it is of interest to further investigate this particular point in order to improve prevention, surveillance and treatment, and, ultimately, the patient's outcome. This literature review aims to report the recent literature on aPL-associated native AVF complications.
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页数:14
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