Fe3O4@TiO2 nanoparticles catalyzed and NaBH4 assisted one-pot reductive amination of aldehydes at ambient condition

An operationally convenient and efficient one-pot reductive amination of diversely substituted aldehydes catalyzed by Fe3O4@TiO2 nanoparticles and NaBH4 as a reductant in ethanol at ambient condition is reported in this work. The structural features of Fe3O4@TiO2 nanoparticles are explored by various tools like FT-IR, XRD, TEM, FE-SEM and EDX techniques. The heterogeneous nature, good catalytic potential and reusability are some of the important attributes of the catalyst. The beneficial features of this procedure are one-pot reaction, short reaction time, low catalyst requirement, applicability to wide range of substrates with good yields, milder and simple reaction condition. The structures of synthesized amine derivatives were established by H-1-NMR, C-13-NMR and HR-MS spectral analysis.