Gastric cancer after Bariatric Bypass Surgery. Do they relate? (A Systematic Review)

被引：8

作者：

Doukas, Sotirios G. ^{[1
]}

Doukas, Panagiotis G. ^{[2
]}

Vageli, Dimitra P. ^{[2
]}

Broder, Arkady ^{[1
]}

机构：

[1] St Peters Univ Hosp, Rutgers RWJ Med Sch, Dept Med, Div Gastroenterol & Hepatol, 254 Easton Ave, New Brunswick, NJ 08901 USA

[2] Yale Univ, Departmengt Surg, Sch Med, New Haven, CT 06510 USA

来源：

OBESITY SURGERY | 2023年 / 33卷 / 06期

关键词：

Roux-en-Y; Gastric bypass; Bariatric surgery; Gastric cancer; Stomach cancer; Bile reflux; GASTROINTESTINAL STROMAL TUMOR; EXCLUDED STOMACH; OUTLET OBSTRUCTION; KAPPAB ACTIVATION; BILE REFLUX; ENDOSCOPY; OBESITY; ADENOCARCINOMA; POUCH; ACID;

D O I：

10.1007/s11695-023-06567-6

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Bariatric bypass surgery has been an effective treatment for morbid obesity. However, there is an increasing number of reported cases of gastric cancer after bypass surgery. Our systematic review showed an increasing trend of gastric cancer cases after bariatric bypass surgery in the last decade, mostly located in the excluded stomach (77%) and diagnosed in an advanced stage. In addition to known risk factors such as tobacco smoking (17%), H. pylori infection (6%), and family history of gastric cancer (3%), bile reflux, a recently proposed cancer-promoting factor, was also estimated in 18% of the cases. Our data suggest that gastric cancer risk assessment should be considered before gastric bypass surgery, and further investigations are needed to determine the value of post-operative gastric cancer surveillance.

引用

页码：1876 / 1888

页数：13

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