Prevalence of dementia in India: National and state estimates from a nationwide study

被引：80

作者：

Lee, Jinkook ^{[1
,2
]}

Meijer, Erik ^{[1
]}

Langa, Kenneth M. ^{[3
,4
,5
]}

Ganguli, Mary ^{[6
]}

Varghese, Mathew ^{[7
]}

Banerjee, Joyita ^{[8
]}

Khobragade, Pranali ^{[1
]}

Angrisani, Marco ^{[1
,2
]}

Kurup, Ravi ^{[9
]}

Chakrabarti, Sankha Shubhra ^{[10
]}

Gambhir, Indrajeet Singh ^{[10
]}

Koul, Parvaiz A. ^{[11
]}

Goswami, Debabrata ^{[12
]}

Talukdar, Arunanshu ^{[13
]}

Mohanty, Rashmi Ranjan ^{[14
]}

Yadati, Raju Sathyanarayana ^{[15
]}

Padmaja, Mekala ^{[15
]}

Sankhe, Lalit ^{[16
]}

Rajguru, Chhaya ^{[16
]}

Gupta, Monica ^{[17
]}

Kumar, Govind ^{[18
]}

Dhar, Minakshi ^{[19
]}

Chatterjee, Prasun ^{[8
]}

Singhal, Sunny ^{[8
]}

Bansal, Rishav ^{[8
]}

Bajpai, Swati ^{[8
]}

Desai, Gaurav ^{[8
]}

Rao, Abhijith R. ^{[8
]}

Sivakumar, Palanimuthu T. ^{[7
]}

Muliyala, Krishna Prasad ^{[7
]}

Bhatankar, Swaroop ^{[20
]}

Chattopadhyay, Aparajita ^{[21
]}

Govil, Dipti ^{[21
]}

Pedgaonkar, Sarang ^{[21
]}

Sekher, T. V. ^{[21
]}

Bloom, David E. ^{[22
]}

Crimmins, Eileen M. ^{[23
]}

Dey, Aparajit Ballav ^{[8
]}

机构：

[1] Univ Southern Calif Los Angeles, Ctr Econ & Social Res, Los Angeles, CA USA

[2] Univ Southern Calif Los Angeles, Dept Econ, Los Angeles, CA USA

[3] Univ Michigan, Dept Internal Med, Ann Arbor, MI USA

[4] Vet Affairs, Ctr Clin Management Res, Ann Arbor, MI USA

[5] Univ Michigan, Inst Social Res, Ann Arbor, MI USA

[6] Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA

[7] Natl Inst Mental Hlth & Neurosci, Dept Psychiat, Bengaluru, India

[8] All India Inst Med Sci, Dept Geriatr Med, New Delhi, India

[9] Govt Med Coll, Dept Med, Thiruvananthapuram, India

[10] Banaras Hindu Univ, Inst Med Sci, Dept Geriatr Med, Varanasi, India

[11] Sher Ekashmir Inst Med Sci, Dept Internal & Pulm Med, Srinagar, India

[12] Guwahati Med Coll, Dept Med, Gauhati, India

[13] Med Coll, Dept Geriatr Med, Kolkata, India

[14] All India Inst Med Sci, Dept Med, Bhubaneswar, India

[15] Nizams Inst Med Sci, Dept Med, Hyderabad, India

[16] JJ Hosp, Grant Med Coll, Dept Community Med, Mumbai, India

[17] Govt Med Coll & Hosp, Dept Gen Med, Chandigarh, India

[18] Indira Gandhi Inst Med Sci, Dept Med, Patna, India

[19] All India Inst Med Sci, Dept Med, Rishikesh, India

[20] Inst Psychol Hlth, Mumbai, India

[21] Int Inst Populat Sci, Mumbai, India

[22] Harvard TH Chan Sch Publ Hlth, Dept Global Hlth & Populat, Boston, MA USA

[23] Univ Southern Calif Los Angeles, Sch Gerontol, Los Angeles, CA USA

来源：

ALZHEIMERS & DEMENTIA | 2023年 / 19卷 / 07期

基金：

美国国家卫生研究院;

关键词：

Alzheimer's disease and related dementia; Clinical Dementia Rating; cognitive impairment; dementia prevalence; major neurocognitive disorder; ALZHEIMERS-DISEASE; INFORMANT QUESTIONNAIRE; COGNITIVE DECLINE; ELDERLY IQCODE; RISK-FACTORS; POPULATION; KERALA; COMMUNITY; DIAGNOSIS; COUNTRIES;

D O I：

10.1002/alz.12928

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

IntroductionPrior estimates of dementia prevalence in India were based on samples from selected communities, inadequately representing the national and state populations. MethodsFrom the Longitudinal Aging Study in India (LASI) we recruited a sample of adults ages 60+ and administered a rich battery of neuropsychological tests and an informant interview in 2018 through 2020. We obtained a clinical consensus rating of dementia status for a subsample (N = 2528), fitted a logistic model for dementia status on this subsample, and then imputed dementia status for all other LASI respondents aged 60+ (N = 28,949). ResultsThe estimated dementia prevalence for adults ages 60+ in India is 7.4%, with significant age and education gradients, sex and urban/rural differences, and cross-state variation. DiscussionAn estimated 8.8 million Indians older than 60 years have dementia. The burden of dementia cases is unevenly distributed across states and subpopulations and may therefore require different levels of local planning and support. HighlightsThe estimated dementia prevalence for adults ages 60+ in India is 7.4%.About 8.8 million Indians older than 60 years live with dementia.Dementia is more prevalent among females than males and in rural than urban areas.Significant cross-state variation exists in dementia prevalence.

引用

页码：2898 / 2912

页数：15

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