Successful Management of Malignant Pericarditis Using Nivolumab for Metastatic Esophageal Squamous Cell Carcinoma

被引：0

作者：

Uneno, Yu ^{[1
]}

Nomura, Motoo ^{[1
]}

Hosokai, Taisuke ^{[1
]}

Kurakake, Yoshinosuke ^{[1
]}

Fuki, Masayuki ^{[1
]}

Shiomi, Hiroki ^{[2
]}

Takeuchi, Yasuhide ^{[3
]}

Tamaoki, Masashi ^{[1
]}

Yokoyama, Akira ^{[1
]}

Katada, Chikatoshi ^{[1
]}

Muto, Manabu ^{[1
]}

机构：

[1] Kyoto Univ Hosp, Dept Clin Oncol, Kyoto, Japan

[2] Kyoto Univ Hosp, Dept Cardiovasc Med, Kyoto, Japan

[3] Kyoto Univ Hosp, Dept Diagnost Pathol, Kyoto, Japan

来源：

INTERNAL MEDICINE | 2024年 / 63卷 / 05期

关键词：

esophageal cancer; nivolumab; cardiac tamponade; pericarditis; pericardial effusion; pericardial drainage; CARDIAC-TAMPONADE; EFFUSION; CANCER; PERICARDIOCENTESIS; EXPRESSION; CISPLATIN; TUMORS; TRIAL;

D O I：

10.2169/internalmedicine.2041-23

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Esophageal cancer is a malignant disease with a poor prognosis and is one of the most common causes of cardiac metastasis. Malignant pericarditis may cause the repetitive accumulation of pericardial effusion, which can occasionally pose a clinical challenge. We herein report a case of malignant pericarditis in a patient with metastatic esophageal squamous cell carcinoma with cardiac tamponade, which was successfully managed with single pericardial drainage and systemic nivolumab monotherapy. This is the first case report to suggest that systemic therapy with nivolumab is a promising option for the management of malignant pericarditis.

引用

页码：677 / 680

页数：4

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