The Impact of TP53 Mutations and Use of the TP53Mutation-Reactivating Agent APR-246 on Metastatic Castrate-Sensitive Prostate Cancer

被引：0
|
作者：
Hoang, T. [1 ]
Sutera, P. [2 ]
Nguyen, T. [1 ]
Chang, J. H. [3 ]
Jagtap, S. [3 ]
Song, Y. [3 ]
Shetty, A. [3 ]
Chowdhury, D. D. [3 ]
Chan, A. [3 ]
Carrieri, F. A. A. [4 ]
Song, D. [5 ]
DeWeese, T. L. [5 ]
Lafargue, A. [5 ]
Van der Eecken, K. [6 ]
Bunz, F. [7 ]
Ost, P. [8 ]
Tran, P. T. [5 ,9 ]
Deek, M. P. [10 ]
机构：
[1] Johns Hopkins Bloomberg Sch Publ Hlth, Baltimore, MD USA
[2] Johns Hopkins Univ, Sch Med, Baltimore, MD USA
[3] Univ Maryland, Baltimore, MD 21201 USA
[4] Johns Hopkins Univ, Baltimore, MD USA
[5] Johns Hopkins Univ, Sch Med, Dept Radiat Oncol & Mol Radiat Sci, Baltimore, MD USA
[6] Univ Ghent, Ghent, Belgium
[7] Johns Hopkins Med, Baltimore, MD USA
[8] Ghent Univ Hosp, Dept Radiat Oncol, Ghent, Belgium
[9] Univ Maryland, Sch Med, Dept Radiat Oncol, Baltimore, MD 21201 USA
[10] Rutgers Canc Inst New Jersey, Dept Radiat Oncol, New Brunswick, NJ USA
来源：
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2023年 / 117卷 / 02期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2966
引用
收藏
页码：E443 / E443
页数：1
相关论文
共 50 条
  • [1] The impact of TP53 mutations and use of the TP53-mutation-reactivating agent APR-246 on metastatic castrate-sensitive prostate cancer.
    Hoang, Tung
    Sutera, Philip
    Nguyen, Triet
    Chang, Jin Hee
    Jagtap, Shreya
    Song, Yang
    Shetty, Amol
    Chowdhury, Dipanwita
    Chan, Aaron
    Carrieri, Francesca Anna
    Song, Daniel Y.
    DeWeese, Theodore L.
    Lafargue, Audrey
    Van der Eecken, Kim
    Ost, Fred Bunz Piet
    Tran, Phuoc T.
    Deek, Matthew
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [2] TP53 structure-function relationships in metastatic castrate-sensitive prostate cancer and the impact of APR-246 treatment
    Hoang, Tung
    Sutera, Philip
    Nguyen, Triet
    Chang, Jinhee
    Jagtap, Shreya
    Song, Yang
    Shetty, Amol C.
    Chowdhury, Dipanwita D.
    Chan, Aaron
    Carrieri, Francesca A.
    Hathout, Lara
    Ennis, Ronald
    Jabbour, Salma K.
    Parikh, Rahul
    Molitoris, Jason
    Song, Daniel Y.
    DeWeese, Theodore
    Marchionni, Luigi
    Ren, Lei
    Sawant, Amit
    Simone, Nicole
    Lafargue, Audrey
    Van Der Eecken, Kim
    Bunz, Fred
    Ost, Piet
    Tran, Phuoc T.
    Deek, Matthew P.
    PROSTATE, 2024, 84 (01): : 87 - 99
  • [3] Functional genetics of APR-246 rescuable TP53 mutants
    Saunders, Anais
    Tong, Caili
    Karnezis, Anthony N.
    Leiserowitz, Gary S.
    Chein, Jeremy R.
    CANCER RESEARCH, 2024, 84 (06)
  • [4] APR-246 cytotoxic effects are TP53 independent in endometrial cancer cell lines
    Yu, Camilla
    Petty, Aaron
    Vargas, Roberto
    CANCER RESEARCH, 2023, 83 (07)
  • [5] Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53
    Abrams, Stephen L.
    Duda, Przemyslaw
    Akula, Shaw M.
    Steelman, Linda S.
    Follo, Matilde L.
    Cocco, Lucio
    Ratti, Stefano
    Martelli, Alberto M.
    Montalto, Giuseppe
    Emma, Maria Rita
    Cervello, Melchiorre
    Rakus, Dariusz
    Gizak, Agnieszka
    McCubrey, James A.
    CELLS, 2022, 11 (05)
  • [6] Deciphering the Increased Prevalence of TP53 Mutations in Metastatic Prostate Cancer
    Zhang, Wensheng
    Dong, Yan
    Sartor, Oliver
    Zhang, Kun
    CANCER INFORMATICS, 2022, 21
  • [7] Deciphering the Increased Prevalence of TP53 Mutations in Metastatic Prostate Cancer
    Zhang, Wensheng
    Dong, Yan
    Sartor, Oliver
    Zhang, Kun
    CANCER INFORMATICS, 2022, 21
  • [8] Comprehensive analysis of TP53 and SPOP mutations and their impact on survival in metastatic prostate cancer
    Zhou, Jie
    Lai, Yiming
    Peng, Shengmeng
    Tang, Chen
    Chen, Yongming
    Li, Lingfeng
    Huang, Hai
    Guo, Zhenghui
    FRONTIERS IN ONCOLOGY, 2022, 12
  • [9] SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status
    Fujihara, Kenji M.
    Benitez, Mariana Corrales
    Cabalag, Carlos S.
    Zhang, Bonnie Z.
    Ko, Hyun S.
    Liu, David S.
    Simpson, Kaylene J.
    Haupt, Ygal
    Lipton, Lara
    Haupt, Sue
    Phillips, Wayne A.
    Clemons, Nicholas J.
    MOLECULAR CANCER THERAPEUTICS, 2021, 20 (10) : 1858 - 1867
  • [10] Impact of TP53 mutations in breast cancer: Clinicopathological features and prognosisImpact of TP53 mutations in breast CA
    Li, Xuerui
    Chen, Xiaoqing
    Wen, Lingzhu
    Wang, Yulei
    Chen, Bo
    Xue, Yunlian
    Guo, Liping
    Liao, Ning
    THORACIC CANCER, 2020, 11 (07) : 1861 - 1868
12345