Visual outcomes after bevacizumab-based therapy for optic pathway glioma

被引：5
作者：
Siegel, Benjamin I. [1 ,4 ]
Nelson, Daniel [2 ]
Peragallo, Jason H. [2 ]
Macdonald, Tobey J. [1 ]
Wolf, David S. [1 ,3 ]
机构：
[1] Emory Univ, Dept Pediat, Atlanta, GA USA
[2] Emory Univ, Dept Ophthalmol, Atlanta, GA USA
[3] Childrens Healthcare Atlanta, Aflac Canc & Blood Disorders Ctr, Atlanta, GA USA
[4] Emory Univ, Dept Pediat, 1400 Tullie Rd NE, Atlanta, GA 30329 USA
来源：
PEDIATRIC BLOOD & CANCER | 2023年 / 70卷 / 12期
关键词：
Gliomas; low-grade; neuro-oncology; outcomes research; PEDIATRIC-PATIENTS; CHILDREN; VISION;
D O I：
10.1002/pbc.30668
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In optic pathway glioma (OPG), bevacizumab-based therapy (BBT) has promising effects on radiographic tumor burden, but the impact on vision is less clear. This single-institution study characterized visual acuity (VA) and visual field (VF) outcomes in 17 pediatric OPG patients treated with BBT. VA was stable or improved in 14 patients. Nine patients had evaluable VF data, six of whom experienced stability or improvement. Among six patients with vision deterioration as a treatment indication, stable or improved was observed for both VA and VF in five patients. In summary, BBT was associated with favorable visual outcomes in this cohort of patients with OPG.
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收藏
页数：5
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