Suppression of background body signals in whole-body diffusion-weighted imaging for detection of bony metastases: a pilot study

被引:0
作者
Eltonbary, Heba Tollah Ahmed Ibrahim [1 ]
Elmashad, Nehal Mohamed [2 ]
Khodair, Sameh Ahmed [3 ]
Abou Khadrah, Rania Sobhy [4 ]
机构
[1] Tanta Univ, Tanta Univ Hosp, Dept Radiol, Fac Med, Algish St, Tanta 31511, Gharbia Governo, Egypt
[2] Tanta Univ, Tanta Univ Hosp, Fac Med, Algish St, Tanta, Gharbia Governo, Egypt
[3] Tanta Univ, Tanta Univ Hosp, Fac Med, Algish St, Tanta 31511, Gharbia Governo, Egypt
[4] Tanta Univ, Tanta Univ Hosp, Coll Med, Fac Med,Radiol Dept, 15 Ebn Elphared St, Tanta 31511, Gharbia Governo, Egypt
关键词
Whole-body; Diffusion WI; Metastasis; Background signals suppression; MAGNETIC-RESONANCE; MARROW INVOLVEMENT; MRI; CANCER; PET/CT;
D O I
10.1186/s43055-023-01012-1
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
BackgroundWhole-body diffusion-weighted magnetic resonance is being developed as a tool for assessing tumor spread. Patients with known primary tumors require meticulous evaluation to assess metastasis for better staging; we attempted to detect bony metastasis without radiation exposure. Our study's goal was to use whole-body diffusion-weighted imaging with background body signal suppression (WB-DWBIS) to evaluate bony metastasis in confirmed patients who have primary tumors.ResultsOur study included 90 patients with known primary cancer, 10 patients were excluded as they had no bony metastasis, from 80 patients: 36 (45.0%) having one site of metastasis, 36 (45%) having two sites of metastasis, and 8 (10.0%) having three sites of metastasis. 56 (70.0%) of the metastasis sites were bony metastasis, and 76 were mixed both bony and non-bony, including 32(40.0%) lung, 16 (20.0%) liver, and 28 (35%) lymph nodes. Sensitivity of bone scanning in detecting metastasis was as follows: 95.1% sensitivity and 92.0% accuracy, while that of whole-body diffusion-weighted image with background signals suppression was 94.8% sensitivity and 91.7% accuracy, WB-DWBIS inter-observer agreement in the detection of bony metastatic deposits in cancer patients was good (0.7 45, agreement = 93.2%).ConclusionsUsing WB-DWBIS images, bone lesion identification and characterization (site and number) were improved, producing outcomes similar to bone scanning without the use of ionizing radiation.
引用
收藏
页数:10
相关论文
共 50 条
[41]   Whole-Body MRI Virtual Autopsy Using Diffusion-weighted Imaging With Background Suppression (DWIBS) at 3 T in a Child Succumbing to Chordoma [J].
Andronikou, Savvas ;
Kemp, Marnie L. ;
Meiring, Michelle .
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2017, 39 (02) :133-136
[42]   Diffusion-weighted imaging as part of hybrid PET/MRI protocols for whole-body cancer staging: Does it benefit lesion detection? [J].
Buchbender, Christian ;
Hartung-Knemeyer, Verena ;
Beiderwellen, Karsten ;
Heusch, Philipp ;
Kuehl, Hilmar ;
Lauenstein, Thomas C. ;
Forsting, Michael ;
Antoch, Gerald ;
Heusner, Till A. .
EUROPEAN JOURNAL OF RADIOLOGY, 2013, 82 (05) :877-882
[43]   Whole body diffusion weighted imaging with background suppression in pachydermoperiostosis: a case report [J].
Khalil, Georges ;
Nawfal, Georges ;
Mikhael, Elio ;
Hage, Karl .
CLINICAL IMAGING, 2022, 84 :38-42
[44]   Whole-Body Diffusion Tensor Imaging: A Feasibility Study [J].
Kenkel, David ;
von Spiczak, Jochen ;
Wurnig, Moritz C. ;
Filli, Lukas ;
Steidle, Guenter ;
Wyss, Michael ;
Boss, Andreas .
JOURNAL OF COMPUTER ASSISTED TOMOGRAPHY, 2016, 40 (01) :183-188
[45]   Impact of Liver and Whole-Body Diffusion-Weighted MRI for Neuroendocrine Tumors on Patient Management: A Pilot Study [J].
Moryoussef, Frederick ;
de Mestier, Louis ;
Belkebir, Mohamed ;
Deguelte-Lardiere, Sophie ;
Brixi, Hedia ;
Kianmanesh, Reza ;
Hoeffel, Christine ;
Cadiot, Guillaume .
NEUROENDOCRINOLOGY, 2017, 104 (03) :264-272
[46]   Effect of gadolinium injection on diffusion-weighted imaging with background body signal suppression (DWIBS) imaging of breast lesions [J].
Moschetta, Marco ;
Telegrafo, Michele ;
Rella, Leonarda ;
Lanora, Amato Antonio Stabile ;
Angelelli, Giuseppe .
MAGNETIC RESONANCE IMAGING, 2014, 32 (10) :1242-1246
[47]   Whole-Body Diffusion-weighted MR Imaging in Cancer: Current Status and Research Directions [J].
Padhani, Anwar R. ;
Koh, Dow-Mu ;
Collins, David J. .
RADIOLOGY, 2011, 261 (03) :700-718
[48]   Staging of uterine cervical carcinoma: whole-body diffusion-weighted magnetic resonance imaging [J].
Yun B. Chen ;
Chun M. Hu ;
Gui L. Chen ;
Dan Hu ;
Jiang Liao .
Abdominal Imaging, 2011, 36 :619-626
[49]   Whole-body diffusion-weighted imaging in oncology. Technical aspects and practical relevance [J].
Kalkmann, J. ;
Lauenstein, T. ;
Stattaus, J. .
RADIOLOGE, 2011, 51 (03) :215-219
[50]   A comparative study: Diffusion weighted whole body imaging with background body signal suppression and hybrid Positron Emission Computed Tomography on detecting lesions in oncologic clinics [J].
Wang, Nianfei ;
Zhang, Mingjun ;
Sun, Tong ;
Chen, Huaidong ;
Huang, Zhonglian ;
Yan, Long ;
Wang, Longsheng ;
Li, Fei ;
Chen, Zhendong .
EUROPEAN JOURNAL OF RADIOLOGY, 2012, 81 (07) :1662-1666