Objective: To determine if increasing obstructive sleep apnea syndrome (OSAS) severity, as determined by preoperative polysomnography data, is an independent risk for respiratory complications and level of follow-up care after adenotonsillectomy or tonsillectomy. Methods: A retrospective analysis of patients <= 21 years of age with severe OSAS (obstructive apnea-hypopnea index [OAHI] >10) undergoing adenotonsillectomy or tonsillectomy. Patients were categorized based on preoperative polysomnography data (PSG). Outcome measures including respiratory complications were collected via chart review. Logistic regression was used in the analysis of all parameters, and Wilcoxon Rank Sum tests were used for analysis of both OAHI and oxygen saturation nadir as continuous variables. All surgeries were performed at Johns Hopkins Hospital, a tertiary care center. Results: We identified 358 patients with severe OSAS who had adenotonsillectomy or tonsillectomy. OAHI >40 and oxygen saturation nadir <80% were significantly associated with postoperative respiratory complications. Increasing OAHI and O2 saturation <80% was each associated with unplanned continuous positive airway pressure (CPAP) initiations postoperatively. There was no association between hypercarbia and presence of any complications. Conclusion: Patients with very severe OSAS (preoperative OAHI >= 40) as determined by preoperative PSG may be at higher risk of developing respiratory complications postoperatively. However, there does not appear to be a linear association with increasing severity of OAHI on regression analysis. Further research is needed to understand factors associated with complications in severe and very severe OAHI.
机构:
Michigan State Univ, Kalamazoo Ctr Med Studies, Dept Pediat & Human Dev, Kalamazoo, MI USA
Michigan State Univ, Kalamazoo Ctr Med Studies, Dept Internal Med, Kalamazoo, MI USAMichigan State Univ, Kalamazoo Ctr Med Studies, Dept Pediat & Human Dev, Kalamazoo, MI USA
Chhangani, Bantu S.
Melgar, Thomas
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Bronson Ctr Sleep Studies, Paw, MI USAMichigan State Univ, Kalamazoo Ctr Med Studies, Dept Pediat & Human Dev, Kalamazoo, MI USA
Melgar, Thomas
Patel, Dilip
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Michigan State Univ, Kalamazoo Ctr Med Studies, Dept Pediat & Human Dev, Kalamazoo, MI USAMichigan State Univ, Kalamazoo Ctr Med Studies, Dept Pediat & Human Dev, Kalamazoo, MI USA
机构:
Tel Aviv Univ, Dana Childrens Hosp, Tel Aviv Med Ctr, Sleep Disorders Ctr, IL-64239 Tel Aviv, IsraelTel Aviv Univ, Dana Childrens Hosp, Tel Aviv Med Ctr, Sleep Disorders Ctr, IL-64239 Tel Aviv, Israel
Tauman, Riva
Gozal, David
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Univ Chicago, Comer Childrens Hosp, Pritzker Sch Med, Dept Pediat, Chicago, IL 60637 USATel Aviv Univ, Dana Childrens Hosp, Tel Aviv Med Ctr, Sleep Disorders Ctr, IL-64239 Tel Aviv, Israel