Is it time for a precision health approach to the management of newborn hyperbilirubinemia?

被引：2

作者：

Stevenson, David K. ^{[1
]}

Wells, Grant S. ^{[2
]}

Wong, Ronald J. ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Pediat, Div Neonatal & Dev Med, Stanford, CA 94305 USA

[2] Stanford Univ, Stanford Maternal & Child Hlth Res Inst, Sch Med, Stanford, CA USA

来源：

JOURNAL OF PERINATOLOGY | 2024年 / 44卷 / 06期

关键词：

ZINC-PROTOPORPHYRIN; BILIRUBIN PRODUCTION; SEVERE JAUNDICE; TERM NEWBORNS; HEMOLYSIS; HEME; INHIBITOR; PREDICTION; INFANTS; RISK;

D O I：

10.1038/s41372-024-01941-3

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Newborn hyperbilirubinemia during the first two weeks of life is one of most common problems requiring management decisions by a pediatrician. However, high bilirubin levels in the circulation have been associated with neurologic injury under a variety of conditions encountered in the newborn infant, such as hemolysis. The risk for developing dangerous hyperbilirubinemia is multifactorial and is determined by a complex set of factors related to a newborn infant's genetic capacities as well as intra- and extrauterine exposures. To this end, a precision health approach based on the integration of prenatal genetic and postnatal diagnostic measures might improve the management of neonatal hyperbilirubinemia.

引用

页码：920 / 923

页数：4

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