Is it time for a precision health approach to the management of newborn hyperbilirubinemia?

被引：0
|
作者：
Stevenson, David K. [1 ]
Wells, Grant S. [2 ]
Wong, Ronald J. [1 ]
机构：
[1] Stanford Univ, Sch Med, Dept Pediat, Div Neonatal & Dev Med, Stanford, CA 94305 USA
[2] Stanford Univ, Stanford Maternal & Child Hlth Res Inst, Sch Med, Stanford, CA USA
来源：
JOURNAL OF PERINATOLOGY | 2024年 / 44卷 / 06期
关键词：
ZINC-PROTOPORPHYRIN; BILIRUBIN PRODUCTION; SEVERE JAUNDICE; TERM NEWBORNS; HEMOLYSIS; HEME; INHIBITOR; PREDICTION; INFANTS; RISK;
D O I：
10.1038/s41372-024-01941-3
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Newborn hyperbilirubinemia during the first two weeks of life is one of most common problems requiring management decisions by a pediatrician. However, high bilirubin levels in the circulation have been associated with neurologic injury under a variety of conditions encountered in the newborn infant, such as hemolysis. The risk for developing dangerous hyperbilirubinemia is multifactorial and is determined by a complex set of factors related to a newborn infant's genetic capacities as well as intra- and extrauterine exposures. To this end, a precision health approach based on the integration of prenatal genetic and postnatal diagnostic measures might improve the management of neonatal hyperbilirubinemia.
引用
收藏
页码：920 / 923
页数：4
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