Synthesis of Chiral α-Aryl Ketones by Photoredox/Nickel-Catalyzed Enantioconvergent Acyl Cross-Coupling with Organotrifluoroborate

被引：5
|
作者：
Wang, Weichen [1 ,2 ]
Shen, Chaoren [1 ,2 ]
Zhang, Linli [1 ,2 ]
Dong, Kaiwu [1 ,2 ]
机构：
[1] East China Normal Univ, Shanghai Frontiers Sci Ctr Mol Intelligent Synth, Sch Chem & Mol Engn, Shanghai 200062, Peoples R China
[2] East China Normal Univ, Sch Chem & Mol Engn, Shanghai Key Lab Green Chem & Chem Proc, Shanghai 200062, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 04期
基金：
国家重点研发计划;
关键词：
TERTIARY ALKYL; LIGHT; COMPLEXES; ARYLATION; INSERTION; ACIDS;
D O I：
10.1021/acs.orglett.3c04004
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Photoredox/nickel-catalyzed enantioconvergent acyl cross-coupling of carboxylic derivatives with racemic secondary organotrifluoroborate was developed for the synthesis of an enolizable chiral alpha-aryl ketone under mild neutral conditions. Moderate to high yields and good enantioselectivities were achieved.
引用
收藏
页码：850 / 854
页数：5
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