Impact of cervical lymph node metastasis on transoral surgery for hypopharyngeal squamous cell carcinoma: A retrospective multicenter study

被引：0

作者：

Ushiro, Koji ^{[1
,16
]}

Watanabe, Yoshiki ^{[2
]}

Kishimoto, Yo ^{[3
]}

Kawai, Yoshitaka ^{[3
]}

Fujimura, Shintaro ^{[3
]}

Asato, Ryo ^{[1
]}

Tsujimura, Takashi ^{[4
]}

Hori, Ryusuke ^{[5
,6
,7
]}

Kumabe, Yohei ^{[8
]}

Yasuda, Kaori ^{[8
]}

Tamaki, Hisanobu ^{[9
]}

Iki, Takehiro ^{[9
]}

Kitani, Yoshiharu ^{[10
]}

Kurata, Keisuke ^{[10
]}

Kojima, Tsuyoshi ^{[3
,7
]}

Takata, Kuniaki ^{[7
]}

Kada, Shinpei ^{[11
]}

Takebayashi, Shinji ^{[12
]}

Shinohara, Shogo ^{[13
]}

Hamaguchi, Kiyomi ^{[3
,13
]}

Miyazaki, Masakazu ^{[14
]}

Ikenaga, Tadashi ^{[14
]}

Maetani, Toshiki ^{[15
]}

Harada, Hiroyuki ^{[15
]}

Haji, Tomoyuki ^{[9
]}

Omori, Koichi ^{[3
]}

机构：

[1] Natl Hosp Org Kyoto Med Ctr, Dept Otolaryngol Head & Neck Surg, Kyoto, Japan

[2] Japanese Red Cross Osaka Hosp, Dept Otolaryngol Head & Neck Surg, Osaka, Japan

[3] Kyoto Univ, Grad Sch Med, Dept Otolaryngol Head & Neck Surg, Kyoto, Japan

[4] Japanese Red Cross Wakayama Med Ctr, Dept Otolaryngol, Wakayama, Japan

[5] Univ Occupat & Environm Hlth, Dept Otolaryngol Head & Neck Surg, Kitakyushu, Japan

[6] Fujita Hlth Univ, Dept Otolaryngol Head & Neck Surg, Toyoake, Japan

[7] Tenri Hosp, Dept Otolaryngol Head & Neck Surg, Tenri, Japan

[8] Hyogo Prefectural Amagasaki Gen Med Ctr, Dept Otolaryngol Head & Neck Surg, Amagasaki, Japan

[9] Kurashiki Cent Hosp, Dept Otolaryngol Head & Neck Surg, Kurashiki, Japan

[10] Shizuoka Prefectural Gen Hosp, Dept Otolaryngol Head & Neck Surg, Shizuoka, Japan

[11] Japanese Red Cross Otsu Hosp, Dept Otolaryngol Head & Neck Surg, Otsu, Japan

[12] Shiga Gen Hosp, Dept Otolaryngol Head & Neck Surg, Moriyama, Japan

[13] Kobe City Med Ctr Gen Hosp, Dept Otolaryngol Head & Neck Surg, Kobe, Japan

[14] Nara Prefecture Gen Med Ctr, Dept Otolaryngol Head & Neck Surg, Nara, Japan

[15] Kitano Hosp, Med Res Inst, Dept Otolaryngol Head & Neck Surg, Osaka, Japan

[16] Natl Hosp Org Kyoto Med Ctr, Dept Otolaryngol Head & Neck Surg, 1-1 Mukaihata-cho,Fukakusa,Fushimi Ku, Kyoto 6128555, Japan

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2024年 / 46卷 / 08期

关键词：

adjuvant therapy; cervical lymph node metastasis; hypopharyngeal cancer; multi-institutional retrospective study; transoral surgery; ROBOTIC SURGERY; LASER MICROSURGERY; FUNCTIONAL OUTCOMES; CANCER; RADIOTHERAPY; LARYNX; HEAD;

D O I：

10.1002/hed.27666

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

BackgroundHypopharyngeal carcinoma is likely to spread to the lymph nodes, but there is no established strategy for management in transoral surgery.MethodsWe compared oncologic and functional outcomes in a retrospective multicenter study of patients who underwent transoral surgery for hypopharyngeal carcinoma between 2015 and 2021.ResultsTwo-hundred and thirty-two patients were included. Comparing patients with and without adjuvant radiotherapy, 3-year regional recurrence-free survival (RRFS) was not significantly different in pN2b and pN2c, but was significantly worse in pN3b without adjuvant radiotherapy. In patients without neck dissection, the 3-year RRFS was 85.6%, 76.8%, and 70.0% for T1, T2, and T3 primary lesions, respectively, and was significantly worse for T2 or higher (p = 0.035).ConclusionsIn the absence of extracapsular invasion, regional control did not deteriorate without adjuvant therapy. If prophylactic neck dissection is not performed, careful follow-up is necessary if the primary lesion is T2 or greater.

引用

页码：1913 / 1921

页数：9

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