Recent Advances in Sodium Magnetic Resonance Imaging and Its Future Role in Kidney Disease

被引：6
作者：
Akbari, Alireza [1 ,2 ]
McIntyre, Christopher W. W. [1 ,2 ,3 ]
机构：
[1] Western Univ, Robarts Res Inst, London, ON N6A 3K7, Canada
[2] London Hlth Sci Ctr, Lilibeth Caberto Kidney Clin Res Unit, London, ON N6A 5W9, Canada
[3] Western Univ, Dept Med Pediat & Med Biophys, London, ON N6A 3K7, Canada
来源：
JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 13期
关键词：
chronic kidney disease; hypertension; inflammation; sodium MRI; skin; heart; kidney; corticomedullary gradient; myocardium; functional sodium MRI; DECOMPENSATED HEART-FAILURE; 11TH CONSENSUS CONFERENCE; IMPLANTABLE CARDIOVERTER-DEFIBRILLATORS; LEFT-VENTRICULAR HYPERTROPHY; ENHANCER-BINDING PROTEIN; INSULIN-RESISTANCE; BLOOD-PRESSURE; TISSUE SODIUM; CARDIOVASCULAR-DISEASE; NA+ STORAGE;
D O I：
10.3390/jcm12134381
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Sodium imbalance is a hallmark of chronic kidney disease (CKD). Excess tissue sodium in CKD is associated with hypertension, inflammation, and cardiorenal disease. Sodium magnetic resonance imaging (Na-23 MRI) has been increasingly utilized in CKD clinical trials especially in the past few years. These studies have demonstrated the association of excess sodium tissue accumulation with declining renal function across whole CKD spectrum (early- to end-stage), biomarkers of systemic inflammation, and cardiovascular dysfunction. In this article, we review recent advances of Na-23 MRI in CKD and discuss its future role with a focus on the skin, the heart, and the kidney itself.
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页数：16
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共 134 条
[91]  
Palevsky PM, 2008, NEW ENGL J MED, V359, P7, DOI 10.1056/NEJMoa0802639
[92]   RELATIONSHIP BETWEEN URINARY CONCENTRATING ABILITY, ARGININE VASOPRESSIN IN PLASMA AND BLOOD-PRESSURE AFTER RENAL-TRANSPLANTATION [J].
PEDERSEN, EB ;
DANIELSEN, H ;
NIELSEN, AH ;
KNUDSEN, F ;
JENSEN, T ;
KORNERUP, HJ ;
MADSEN, M .
SCANDINAVIAN JOURNAL OF CLINICAL & LABORATORY INVESTIGATION, 1985, 45 (04) :321-326
[93]   Pruritus: Is there a grain of salty truth? [J].
Penny, Jarrin D. ;
Salerno, Fabio R. ;
Akbari, Alireza ;
McIntyre, Christopher W. .
HEMODIALYSIS INTERNATIONAL, 2021, 25 (01) :E10-E14
[94]   Review on Inflammation Markers in Chronic Kidney Disease [J].
Petreski, Tadej ;
Piko, Nejc ;
Ekart, Robert ;
Hojs, Radovan ;
Bevc, Sebastjan .
BIOMEDICINES, 2021, 9 (02) :1-16
[95]   Increases in intracellular sodium activate transcription and gene expression via the salt-inducible kinase 1 network in an atrial myocyte cell line [J].
Popov, Sergej ;
Venetsanou, Kyriaki ;
Chedrese, P. Jorge ;
Pinto, Vanda ;
Takemori, Hiroshi ;
Franco-Cereceda, Anders ;
Eriksson, Per ;
Mochizuki, Naoki ;
Soares-da-Silva, Patricio ;
Bertorello, Alejandro M. .
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2012, 303 (01) :H57-H65
[96]   Tissue sodium concentrations in chronic kidney disease and dialysis patients by lower leg sodium-23 magnetic resonance imaging [J].
Qirjazi, Elena ;
Salerno, Fabio R. ;
Akbari, Alireza ;
Hur, Lisa ;
Penny, Jarrin ;
Scholl, Timothy ;
McIntyre, Christopher W. .
NEPHROLOGY DIALYSIS TRANSPLANTATION, 2021, 36 (07) :1234-1243
[97]   First-in-Human Experience With Peritoneal Direct Sodium Removal Using a Zero-Sodium Solution A New Candidate Therapy for Volume Overload [J].
Rao, Veena S. ;
Turner, Jeffrey M. ;
Griffin, Matthew ;
Mahoney, Devin ;
Asher, Jennifer ;
Jeon, Sangchoon ;
Yoo, Peter S. ;
Boutagy, Nabil ;
Feher, Attila ;
Sinusas, Albert ;
Wilson, F. Perry ;
Finkelstein, Fredric ;
Testani, Jeffrey M. .
CIRCULATION, 2020, 141 (13) :1043-1053
[98]   Fibrosis imaging with multiparametric proton and sodium MRI in pig injury models [J].
Rasmussen, Camilla W. ;
Bogh, Nikolaj ;
Bech, Sabrina K. ;
Thorsen, Thomas H. ;
Hansen, Esben S. S. ;
Bertelsen, Lotte B. ;
Laustsen, Christoffer .
NMR IN BIOMEDICINE, 2023, 36 (02)
[99]   Sodium MRI of a Human Transplanted Kidney [J].
Rosen, Yael ;
Lenkinski, Robert E. .
ACADEMIC RADIOLOGY, 2009, 16 (07) :886-889
[100]   Defining myocardial tissue abnormalities in end-stage renal failure with cardiac magnetic resonance imaging using native T1 mapping [J].
Rutherford, Elaine ;
Talle, Mohammed A. ;
Mangion, Kenneth ;
Bell, Elizabeth ;
Rauhalammi, Samuli M. ;
Roditi, Giles ;
McComb, Christie ;
Radjenovic, Aleksandra ;
Welsh, Paul ;
Woodward, Rosemary ;
Struthers, Allan D. ;
Jardine, Alan G. ;
Patel, Rajan K. ;
Berry, Colin ;
Mark, Patrick B. .
KIDNEY INTERNATIONAL, 2016, 90 (04) :845-852
567891011121314