Inverse association between stress induced cortisol elevations and negative emotional reactivity to stress in humans

被引：4

作者：

Abercrombie, Heather C. ^{[1
]}

Barnes, Alexandra L. ^{[1
]}

Nord, Elizabeth C. ^{[1
]}

Finley, Anna J. ^{[1
]}

Higgins, Estelle T. ^{[1
,3
]}

Grupe, Daniel W. ^{[1
]}

Rosenkranz, Melissa A. ^{[1
,2
]}

Davidson, Richard J. ^{[1
,2
,3
]}

Schaefer, Stacey M. ^{[1
]}

机构：

[1] Univ Wisconsin, Ctr Hlth Minds, Madison, WI 53703 USA

[2] Univ Wisconsin, Dept Psychiat, Madison, WI USA

[3] Univ Wisconsin, Dept Psychol, Madison, WI USA

来源：

STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS | 2023年 / 26卷 / 01期

关键词：

Cortisol; glucocorticoids; emotion; negative affect; stress; TSST; FEAR;

D O I：

10.1080/10253890.2023.2174780

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Greater cortisol reactivity to stress is often assumed to lead to heightened negative affective reactivity to stress. Conversely, a growing body of evidence demonstrates mood-protective effects of cortisol elevations in the context of acute stress. We administered a laboratory-based stressor, the Trier Social Stress Test (TSST), and measured cortisol and emotional reactivity in 68 adults (48 women) between the ages of 25 and 65. In accordance with our pre-registered hypothesis () and prior research, negative affective reactivity was inversely related to cortisol reactivity assessed immediately after the stressor. We found that greater cortisol response to acute stress is associated with smaller increases in negative affect, consistent with mood-protective effects of cortisol elevations in response to acute stress.

引用

页数：6

共 20 条

[1]

[Anonymous], 2018, OXFORD HDB INTEGRATI

[2] Alterations in Systemic and Cognitive Glucocorticoid Sensitivity in Depression [J].

Gaffey, Allison E. ;

Walsh, Erin C. ;

Ladd, Charlotte O. ;

Hoks, Roxanne M. ;

Abercrombie, Heather C. .

BIOLOGICAL PSYCHIATRY-COGNITIVE NEUROSCIENCE AND NEUROIMAGING, 2019, 4 (03) :310-320

[3] Cortisol response to an experimental stress paradigm prospectively predicts long-term distress and resilience trajectories in response to active police service [J].

Galatzer-Levy, Isaac R. ;

Steenkamp, Maria M. ;

Brown, Adam D. ;

Qian, Meng ;

Inslicht, Sabra ;

Henn-Haase, Clare ;

Otte, Christian ;

Yehuda, Rachel ;

Neylan, Thomas C. ;

Marmar, Charles R. .

JOURNAL OF PSYCHIATRIC RESEARCH, 2014, 56 :36-42

[4] Missing Data Analysis: Making It Work in the Real World [J].

Graham, John W. .

ANNUAL REVIEW OF PSYCHOLOGY, 2009, 60 :549-576

[5] The physiological response to Trier Social Stress Test relates to subjective measures of stress during but not before or after the test [J].

Hellhammer, Juliane ;

Schubert, Melanie .

PSYCHONEUROENDOCRINOLOGY, 2012, 37 (01) :119-124

[6] Mood changes in response to psychosocial stress in healthy young women: Effects of pretreatment with cortisol [J].

Het, Serkan ;

Wolf, Oliver T. .

BEHAVIORAL NEUROSCIENCE, 2007, 121 (01) :11-20

[7] Stress-Induced Cortisol Level Elevations Are Associated With Reduced Negative Affect After Stress: Indications for a Mood-Buffering Cortisol Effect [J].

Het, Serkan ;

Schoofs, Daniela ;

Rohleder, Nicolas ;

Wolf, Oliver T. .

PSYCHOSOMATIC MEDICINE, 2012, 74 (01) :23-32

[8] Corticosteroids and the brain [J].

Joels, Marian .

JOURNAL OF ENDOCRINOLOGY, 2018, 238 (03) :R121-R130

[9] SALIVARY CORTISOL IN PSYCHONEUROENDOCRINE RESEARCH - RECENT DEVELOPMENTS AND APPLICATIONS [J].

KIRSCHBAUM, C ;

HELLHAMMER, DH .

PSYCHONEUROENDOCRINOLOGY, 1994, 19 (04) :313-333

[10] THE TRIER SOCIAL STRESS TEST - A TOOL FOR INVESTIGATING PSYCHOBIOLOGICAL STRESS RESPONSES IN A LABORATORY SETTING [J].

KIRSCHBAUM, C ;

PIRKE, KM ;

HELLHAMMER, DH .

NEUROPSYCHOBIOLOGY, 1993, 28 (1-2) :76-81

← 1 2 →