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Recent advances of nanotechnology in the treatment and diagnosis of polycystic ovary syndrome
被引:8
|作者:
Javid-Naderi, Mohammad Javad
[1
,2
]
Mahmoudi, Ali
[1
,2
]
Kesharwani, Prashant
[3
,4
]
Jamialahmadi, Tannaz
[5
]
Sahebkar, Amirhossein
[5
,6
,7
]
机构:
[1] Mashhad Univ Med Sci, Student Res Comm, Fac Med, Mashhad, Iran
[2] Mashhad Univ Med Sci, Fac Med, Dept Med Biotechnol & Nanotechnol, Mashhad, Iran
[3] Jamia Hamdard, Sch Pharmaceut Educ & Res, Dept Pharmaceut, New Delhi, India
[4] Saveetha Inst Med & Tech Sci, Saveetha Dent Coll, Ctr Transdisciplinary Res, Dept Pharmacol, Chennai, India
[5] Mashhad Univ Med Sci, Appl Biomed Res Ctr, Mashhad, Iran
[6] Mashhad Univ Med Sci, Pharmaceut Technol Inst, Biotechnol Res Ctr, Mashhad, Iran
[7] Mashhad Univ Med Sci, Sch Pharm, Dept Biotechnol, Mashhad, Iran
关键词:
PCOS;
Nanomedicine;
Diagnosis;
Therapy;
Drug delivery;
Nanotechnology;
SYNDROME PCOS;
INSULIN-RESISTANCE;
OXIDATIVE STRESS;
IN-VITRO;
CURCUMIN;
WOMEN;
NANOPARTICLES;
METFORMIN;
EXTRACT;
PATHOGENESIS;
D O I:
10.1016/j.jddst.2022.104014
中图分类号:
R9 [药学];
学科分类号:
1007 ;
摘要:
Polycystic ovary syndrome (PCOS) is an infertility-causing disease commonly occurring in reproductive age females. As the name indicates, the condition involves ovaries with many cysts. The global prevalence of PCOS in women is between 15% and 20%. Several metabolic and endocrine problems are associated with this illness. Nanotechnology has given birth to new aspirations for addressing today's human concerns, and it has been employed to aid prevention, diagnosis, and treatment of PCOS. Nanomaterials have intriguing traits and ca-pacities, such as desired size, faster transit through biological barriers, greater solubility, and enhanced reac-tivity. This study aims to provide a brief overview of nanomaterials and nanotechnology applications in treating and diagnosing women with PCOS. We first review the studies that harnessed medicines produced based on nanotechnology for treating PCOS. Then, we describe recent approaches in the drug delivery nanosystems in PCOS. Furthermore, we provide information about the protective effects of nanoparticles in this disorder. Lastly, we introduce how this technology might help health keepers in the early detection of PCOS.
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页数:9
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