Hybrid polymeric-metallic foams for bone tissue engineering scaffolds: mechanical properties and biofunctionality evaluations

被引：2
作者：
Mahapatro, Anil [1 ]
Hlaing, Hay Mar [2 ]
Malladi, Lipi [2 ]
Keshavanarayana, Suresh [3 ]
机构：
[1] Wichita State Univ, Dept Biomed Engn, 1845 Fairmount St, Wichita, KS 67260 USA
[2] Wichita State Univ, Dept Ind & Mfg Engn, Wichita, KS USA
[3] Wichita State Univ, Dept Aerosp Engn, Wichita, KS USA
来源：
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS | 2023年 / 72卷 / 02期
关键词：
Polymer foams; scaffolds; bone tissue engineering; biocompatibility; MAGNESIUM; MORPHOLOGY; NIOBIUM; ALLOYS;
D O I：
10.1080/00914037.2021.1990058
中图分类号：
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号：
0805 ; 080501 ; 080502 ;
摘要：
Challenges exist in the applicability of thermoplastic foams as scaffolds for bone tissue engineering including mismatch of mechanical properties. Template assisted electrodeposition was carried out to fabricate hybrid polymeric-metallic foams. Compression test, cytotoxicity and biofunctionality evaluations was performed on polyurethane coated niobium foams to investigate the enhancement of desired properties. Results indicated that ultimate compressive strength of polyurethane foams improved due to the niobium coatings. Biocompatibility evaluations showed that the niobium coated foams were biocompatible. Bio-functionality evaluations showed that the coating of niobium on polyurethane decreases its ability to support osteoblastic cell attachment and proliferation.
引用
收藏
页码：135 / 143
页数：9
相关论文
共 50 条
[31]   Effect of the Addition of Inorganic Fillers on the Properties of Degradable Polymeric Blends for Bone Tissue Engineering [J].
Marecik, Stanislaw ;
Pudelko-Prazuch, Iwona ;
Balasubramanian, Mareeswari ;
Ganesan, Sundara Moorthi ;
Chatterjee, Suvro ;
Pielichowska, Kinga ;
Kandaswamy, Ravichandran ;
Pamula, Elzbieta .
MOLECULES, 2024, 29 (16)
[32]   In vitro blood compatibility and bone mineralization aspects of polymeric scaffold laden with essential oil and metallic particles for bone tissue engineering [J].
Zhang, Zhizhong ;
Zheng, Yu ;
Zhang, Lipeng ;
Mani, Mohan Prasath ;
Jaganathan, Saravana Kumar .
INTERNATIONAL JOURNAL OF POLYMER ANALYSIS AND CHARACTERIZATION, 2019, 24 (06) :504-516
[33]   Evaluating and Modeling the Mechanical Properties of the Prepared PLGA/nano-BCP Composite Scaffolds for Bone Tissue Engineering [J].
Ebrahimian-Hosseinabadi, M. ;
Ashrafizadeh, F. ;
Etemadifar, M. ;
Venkatraman, Subbu S. .
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2011, 27 (12) :1105-1112
[34]   Evaluating and Modeling the Mechanical Properties of the Prepared PLGA/nano-BCP Composite Scaffolds for Bone Tissue Engineering [J].
M EbrahimianHosseinabadi ;
F Ashrafizadeh ;
M Etemadifar ;
Subbu S Venkatraman .
JournalofMaterialsScience&Technology, 2011, 27 (12) :1105-1112
[35]   Design strategies for composite matrix and multifunctional polymeric scaffolds with enhanced bioactivity for bone tissue engineering [J].
Kumari, Shikha ;
Katiyar, Soumya ;
Anand, Aditya ;
Singh, Divakar ;
Singh, Bhisham Narayan ;
Mallick, Sarada Prasanna ;
Mishra, Abha ;
Srivastava, Pradeep .
FRONTIERS IN CHEMISTRY, 2022, 10
[36]   Preparation, structural and mechanical characterization of porous hydroxyapatite-gelatin composite scaffolds for bone tissue engineering [J].
Narbat, Mehdi Kazemzadeh .
PROCEEDINGS OF THE FIFTH IASTED INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING, 2007, :452-457
[37]   Biomimetic electrospun polyurethane matrix composites with tailor made properties for bone tissue engineering scaffolds [J].
Jaganathan, Saravana Kumar ;
Mani, Mohan Prasath ;
Ayyar, Manikandan ;
Rathanasamy, Rajasekar .
POLYMER TESTING, 2019, 78
[38]   Micro-CT-based screening of biomechanical and structural properties of bone tissue engineering scaffolds [J].
Tim Van Cleynenbreugel ;
Jan Schrooten ;
Hans Van Oosterwyck ;
Jos Vander Sloten .
Medical and Biological Engineering and Computing, 2006, 44 :517-525
[39]   Micro-CT-based screening of biomechanical and structural properties of bone tissue engineering scaffolds [J].
Van Cleynenbreugel, Tim ;
Schrooten, Jan ;
Van Oosterwyck, Hans ;
Sloten, Jos Vander .
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 2006, 44 (07) :517-525
[40]   Physicochemical properties and cytocompatibility assessment of non-degradable scaffolds for bone tissue engineering applications [J].
Pereira, H. ;
Cengiz, I. F. ;
Maia, F. R. ;
Bartolomeu, F. ;
Oliveira, J. M. ;
Reis, R. L. ;
Silva, F. S. .
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2020, 112
12345