Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy

被引:0
作者
Bui, Thi Ngoc Hang [1 ]
Large, Matthew [1 ]
Poder, Joel [1 ,2 ,3 ]
Bucci, Joseph [1 ,2 ]
Bianco, Edoardo [4 ,5 ]
Giampaolo, Raffaele Aaron [4 ,5 ]
Rivetti, Angelo [5 ]
Da Rocha Rolo, Manuel [5 ]
Pastuovic, Zeljko [6 ]
Corradino, Thomas [7 ,8 ]
Pancheri, Lucio [7 ,8 ]
Petasecca, Marco [1 ]
机构
[1] Univ Wollongong, Ctr Med Radiat Phys, Wollongong, NSW 2522, Australia
[2] St George Canc Care Ctr, Kogarah, NSW 2217, Australia
[3] Univ Sydney, Sch Phys, Camperdown, NSW 2050, Australia
[4] Polytech Univ Turin, Dept Elect & Telecommun, I-10129 Turin, Italy
[5] Ist Nazl Fis Nucl, Sect Turin, I-10125 Turin, Italy
[6] Australian Nucl Sci & Technol Org, Lucas Heights, NSW 2234, Australia
[7] Univ Trento, Dept Ind Engn, I-38123 Trento, Italy
[8] Trento Inst Fundamental Phys & Applicat, Ist Nazl Fis Nucleare, I-38123 Trento, Italy
关键词
brachytherapy; CMOS; source tracking; active pixel; dosimetry; IBIC; PIXEL SENSORS MAPS; IN-VIVO DOSIMETRY; PROSTATE BRACHYTHERAPY; RADIATION-THERAPY; TREATMENT DELIVERY; QUALITY-ASSURANCE; VERIFICATION; SYSTEM;
D O I
10.3390/s24020692
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
We assessed the accuracy of a prototype radiation detector with a built in CMOS amplifier for use in dosimetry for high dose rate brachytherapy. The detectors were fabricated on two substrates of epitaxial high resistivity silicon. The radiation detection performance of prototypes has been tested by ion beam induced charge (IBIC) microscopy using a 5.5 MeV alpha particle microbeam. We also carried out the HDR Ir-192 radiation source tracking at different depths and angular dose dependence in a water equivalent phantom. The detectors show sensitivities spanning from (5.8 +/- 0.021) x 10-8 to (3.6 +/- 0.14) x 10-8 nC Gy-1 mCi-1 mm-2. The depth variation of the dose is within 5% with that calculated by TG-43. Higher discrepancies are recorded for 2 mm and 7 mm depths due to the scattering of secondary particles and the perturbation of the radiation field induced in the ceramic/golden package. Dwell positions and dwell time are reconstructed within +/- 1 mm and 20 ms, respectively. The prototype detectors provide an unprecedented sensitivity thanks to its monolithic amplification stage. Future investigation of this technology will include the optimisation of the packaging technique.
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页数:19
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