Association of hair polychlorinated biphenyls and multiclass pesticides with obesity, diabetes, hypertension and dyslipidemia in NESCAV study

被引:8
作者
Peng, Feng-Jiao [1 ]
Lin, Chia-An [2 ]
Wada, Rin [2 ]
Bodinier, Barbara [2 ]
Iglesias-Gonzalez, Alba [1 ]
Palazzi, Paul [1 ]
Streel, Sylvie [3 ]
Guillaume, Michele [3 ]
Vuckovic, Dragana [2 ]
Chadeau-Hyam, Marc [2 ]
Appenzeller, Brice M. R. [1 ]
机构
[1] Luxembourg Inst Hlth, Dept Precis Hlth, Human Biomonitoring Res Unit, 1 A-B Rue Thomas Edison, L-1445 Strassen, Luxembourg
[2] Imperial Coll London, Sch Publ Hlth, Dept Epidemiol & Biostat, MRC PHE Ctr Environm & Hlth, London, England
[3] Univ Liege, Dept Publ Hlth Sci, Liege, Belgium
关键词
CVD risk factors; Hair analysis; Pollutant mixture; Persistent organic pollutants; Currently used pesticides; PERSISTENT ORGANIC POLLUTANTS; HIGH-FAT DIET; ORGANOCHLORINE PESTICIDES; INSULIN-RESISTANCE; CHRONIC EXPOSURE; NATIONAL-HEALTH; LIPID-LEVELS; WEIGHT-GAIN; SERUM; BLOOD;
D O I
10.1016/j.jhazmat.2023.132637
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
Obesity, diabetes, hypertension and dyslipidemia are well-established risk factors for cardiovascular diseases (CVDs), and have been associated with exposure to persistent organic pollutants. However, studies have been lacking as regards effects of non-persistent pesticides on CVD risk factors. Here, we investigated whether background chronic exposure to polychlorinated biphenyls (PCBs) and multiclass pesticides were associated with the prevalence of these CVD risk factors in 502 Belgian and 487 Luxembourgish adults aged 18-69 years from the Nutrition, environment and cardiovascular health (NESCAV) study 2007-2013. We used hair analysis to evaluate the chronic internal exposure to three PCBs, seven organochlorine pesticides (OCs) and 18 non-persistent pes-ticides. We found positive associations of obesity with hexachlorobenzene (HCB), 8-hexachlorocyclohexane (8-HCH) and chlorpyrifos, diabetes with pentachlorophenol (PCP), fipronil and fipronil sulfone, hypertension with PCB180 and chlorpyrifos, and dyslipidemia with diflufenican and oxadiazon, among others. However, we
引用
收藏
页数:12
相关论文
共 72 条
  • [21] The effects of chemical mixtures on lipid profiles in the Korean adult population: threshold and molecular mechanisms for dyslipidemia involved
    Hai Duc Nguyen
    Oh, Hojin
    Kim, Min-Sun
    [J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 2022, 29 (26) : 39182 - 39208
  • [22] Nonoccupational Exposure to Pyrethroids and Risk of Coronary Heart Disease in the Chinese Population
    Han, Jiajun
    Zhou, Liqin
    Luo, Mai
    Liang, Yiran
    Zhao, Wenting
    Wang, Peng
    Zhou, Zhiqiang
    Liu, Donghui
    [J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 51 (01) : 664 - 670
  • [23] Hair versus urine for the biomonitoring of pesticide exposure: Results from a pilot cohort study on pregnant women
    Hardy, Emilie M.
    Dereumeaux, Clementine
    Guldner, Laurence
    Briand, Olivier
    Vandentorren, Stephanie
    Oleko, Amivi
    Zaros, Cecile
    Appenzeller, Brice M. R.
    [J]. ENVIRONMENT INTERNATIONAL, 2021, 152
  • [24] Multi-residue analysis of organic pollutants in hair and urine for matrices comparison
    Hardy, Emilie M.
    Duca, Radu C.
    Salquebre, Guillaume
    Appenzeller, Brice M. R.
    [J]. FORENSIC SCIENCE INTERNATIONAL, 2015, 249 : 6 - 19
  • [25] ANATOMY AND PHYSIOLOGY OF HAIR
    HARKEY, MR
    [J]. FORENSIC SCIENCE INTERNATIONAL, 1993, 63 (1-3) : 9 - 18
  • [26] Blood pressure in relation to contamination by polychlorobiphenyls and organochlorine pesticides: Results from a population-based study in the Canary Islands (Spain)
    Henriquez-Hernandez, Luis A.
    Luzardo, Octavio P.
    Zumbado, Manuel
    Camacho, Maria
    Serra-Majem, Lluis
    Alvarez-Leon, Eva E.
    Boada, Luis D.
    [J]. ENVIRONMENTAL RESEARCH, 2014, 135 : 48 - 54
  • [27] Exposure to the pesticide DDT and risk of diabetes and hypertension: Systematic review and meta-analysis of prospective studies
    Hernandez-Mariano, Jose Angel
    Baltazar-Reyes, Mary Carmen
    Salazar-Martinez, Eduardo
    Cupul-Uicab, Lea A.
    [J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2022, 239
  • [28] Exposure to p,p′-dichlorodiphenyldichloroethylene (DDE) induces fasting hyperglycemia without insulin resistance in male C57BL/6H mice
    Howell, George E., III
    Meek, Edward
    Kilic, Jessica
    Mohns, Mariel
    Mulligan, Charlee
    Chambers, Janice E.
    [J]. TOXICOLOGY, 2014, 320 : 6 - 14
  • [29] Longitudinal, association of biomarkers of pesticide exposure with cardiovascular disease risk factors in youth with diabetes
    Kaur, Navdep
    Starling, Anne P.
    Calafat, Antonia M.
    Sjodin, Andreas
    Clouet-Foraison, Noemie
    Dolan, Lawrence M.
    Imperatore, Giuseppina
    Jensen, Elizabeth T.
    Lawrence, Jean M.
    Ospina, Maria
    Pihoker, Catherine
    Taylor, Kyla W.
    Turley, Christine
    Dabelea, Dana
    Jaacks, Lindsay M.
    [J]. ENVIRONMENTAL RESEARCH, 2020, 181 (181)
  • [30] Perinatal DDT Exposure Induces Hypertension and Cardiac Hypertrophy in Adult Mice
    La Merrill, Michele A.
    Sethi, Sunjay
    Benard, Ludovic
    Moshier, Erin
    Haraldsson, Borje
    Buettner, Christoph
    [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2016, 124 (11) : 1722 - 1727