Electrochemical Radical Reaction Construction of C-C Bonds: Access to 1,4-Dicarbonyl Compounds from Enol Acetates and 1,3-Diketones

被引：5

作者：

Wu, Fan ^{[1
]}

Liu, Shengjun ^{[1
]}

Lv, Xiaoqing ^{[1
]}

Pan, Mei ^{[1
]}

Liu, Xiaoqin ^{[1
]}

Zhang, Jinpeng ^{[2
]}

Rong, Liangce ^{[1
]}

机构：

[1] Jiangsu Normal Univ, Sch Chem & Mat Sci, Xuzhou 221116, Jiangsu, Peoples R China

[2] Xuzhou Med Univ, Sch Publ Hlth, Key Lab Environm & Hlth, Xuzhou 221004, Jiangsu, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 19期

基金：

中国国家自然科学基金;

关键词：

ONE-POT SYNTHESIS; MODULAR SYNTHESIS; 1,2-DIKETONES; WATER; CATALYSIS; ALCOHOLS; KETONES;

D O I：

10.1021/acs.joc.3c01407

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

As important substrates for the construction of heterocycles, a simple and efficient approach for synthesis of 1,4-diones is highly desirable. In this work, novel and efficient electrochemical radical reactions of enol acetates and 1,3-diketones have been developed to successfully achieve 1,4-diketones under catalyst-free and oxidant-free conditions. The wide range of substrates, good group tolerance, and simple operation process make the approach have important practical value. Moreover, the obtained 1,4-diketones can be easily further transformed to pyrrole and furan derivatives.

引用

页码：13749 / 13759

页数：11