COVID-19 and Diabetes Mellitus: Mutual Interplay of Two Diseases

被引：0

作者：

Krumpolec, Patrik ^{[1
]}

Kodada, Dominik ^{[1
,2
]}

Nyariova, Nikola ^{[1
,2
]}

Repiska, Vanda ^{[2
]}

Minarik, Gabriel ^{[1
]}

机构：

[1] Medirex Grp Acad npo, Novozamocka 67, Nitra, Slovakia

[2] Comenius Univ, Fac Med, Dept Clin Biol Genet & Clin Genet, Sasinkova 4, Bratislava, Slovakia

来源：

CURRENT DIABETES REVIEWS | 2023年 / 19卷 / 09期

关键词：

COVID-19; diabetes; Angiotensin-Converting Enzyme 2; immunity; inflammation; diabetes mellitus; CORONAVIRUS; ACE2; INFLAMMATION; INFECTION; PNEUMONIA; TYPE-1;

D O I：

10.2174/1573399819666220913113146

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Currently, when the world is fighting against the rapidly spreading pandemic of COVID-19, the silent epidemic of diabetes should not be set aside. In comparison, while COVID19 led to about 6 million deaths in 2021, diabetes caused 6.7 million deaths in the same year. Diabetes mellitus is a serious risk factor for worse outcomes in COVID-19 patients. Moreover, it seems that there is a bidirectional relationship between pre-existing diabetes pandemic and the rapidly spreading COVID-19 pandemic.In this article, we summarize mechanisms by which SARS-CoV-2 infects the host cell and discuss the bidirectional relationship between diabetes and COVID-19. We also focus on clinical variables in which diabetic patients differ from non-diabetic patients and which could have promising predictive value for the course and outcome of diabetic COVID-19 patients' therapy management.

引用

页码：64 / 70

页数：7

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