Sentinel node identification in laryngeal and pharyngeal carcinoma after flexible endoscopy-guided tracer injection under topical anesthesia: A feasibility study

被引：3

作者：

Driessen, Daphne A. J. J. ^{[1
,5
]}

Arens, Anne I. J. ^{[2
]}

Dijkema, Tim ^{[1
]}

Weijs, Willem L. J. ^{[3
]}

Draaijer, Lisette C. ^{[4
]}

van den Broek, Guido B. ^{[4
]}

Takes, Robert P. ^{[4
]}

Honings, Jimmie ^{[4
]}

Kaanders, Johannes H. A. M. ^{[1
]}

机构：

[1] Radboud Univ Nijmegen, Dept Radiat Oncol, Med Ctr, Nijmegen, Netherlands

[2] Radboud Univ Nijmegen, Dept Med Imaging, Med Ctr, Nijmegen, Netherlands

[3] Radboud Univ Nijmegen, Dept Oral and Maxillofacial Surg & Head & Neck Sur, Med Ctr, Nijmegen, Netherlands

[4] Radboud Univ Nijmegen, Dept Otorhinolaryngol Head & Neck Surg, Med Ctr, Nijmegen, Netherlands

[5] Radboud Univ Nijmegen, Dept Radiat Oncol, Med Ctr, NL-6525 GA Nijmegen, Netherlands

来源：

HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2023年 / 45卷 / 06期

关键词：

flexible endoscopy; laryngeal cancer; office-based procedures; pharyngeal cancer; sentinel lymph node; SQUAMOUS-CELL CARCINOMA; CLINICALLY N0 LARYNGEAL; QUALITY-OF-LIFE; NECK-CANCER; LYMPH-NODES; SPECT-CT; HEAD; BIOPSY; TOXICITY; IMPACT;

D O I：

10.1002/hed.27347

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

BackgroundThe aim of this study was to investigate the feasibility of flexible endoscopy-guided tracer injection for sentinel lymph node (SLN) identification in patients with laryngeal and pharyngeal carcinoma. MethodsSixteen cT1-4N0-2M0 patients with laryngeal or pharyngeal carcinoma underwent intra- and peritumoral [Tc-99m]Tc-nanocolloid injections after topical anesthesia under endoscopic guidance. SPECT-CT scans were performed at two time points. ResultsTracer injection and visualization of SLNs was successful in 15/16 (94%) patients. Median number of tracer injections was 1 intratumoral and 3 peritumoral. The median duration of the endoscopic procedure including tracer injection after biopsy taking was 7 min (range 4-16 min). A total of 28 SLNs were identified which were all visualized on the early and late SPECT-CT. Most SLNs were visualized in neck levels II and III. ConclusionsFlexible endoscopy-guided tracer injection for SLN identification is a feasible and fast procedure in laryngeal and pharyngeal carcinoma patients.

引用

页码：1359 / 1366

页数：8

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