Long non-coding RNAs involved in retinoblastoma

被引：5

作者：

Nasrolahi, Ava ^{[1
]}

Azizidoost, Shirin ^{[2
]}

Radoszkiewicz, Klaudia ^{[3
]}

Najafi, Sajad ^{[4
]}

Ghaedrahmati, Farhoodeh ^{[5
]}

Sheykhi-Sabzehpoush, Mohadeseh ^{[6
]}

Poodineh, Jafar ^{[7
]}

Hajizadeh, Maryam ^{[1
,8
]}

Anbiyaiee, Amir ^{[9
]}

Farzaneh, Maryam ^{[10
]}

Feghhi, Mostafa ^{[1
,8
]}

机构：

[1] Ahvaz Jundishapur Univ Med Sci, Imam Khomeini Hosp Clin Res Dev Unit, Infect Ophthalmol Res Ctr, Ahvaz, Iran

[2] Ahvaz Jundishapur Univ Med Sci, Atherosclerosis Res Ctr, Ahvaz, Iran

[3] Polish Acad Sci, Mossakowski Med Res Inst, Translat Platform Regenerat Med, Warsaw, Poland

[4] Shahid Beheshti Univ Med Sci, Sch Adv Technol Med, Dept Med Biotechnol, Tehran, Iran

[5] Isfahan Univ Med Sci, Sch Med, Dept Immunol, Esfahan, Iran

[6] Ahvaz Jundishapur Univ Med Sci, Sch Med, Dept Immunol, Ahvaz, Iran

[7] Zabol Univ Med Sci, Sch Med, Dept Clin Biochem, Zabol, Iran

[8] Ahvaz Jundishapur Univ Med Sci, Imam Khomeini Hosp, Sch Med, Dept Ophthalmol, Ahvaz, Iran

[9] Ahvaz Jundishapur Univ Med Sci, Sch Med, Dept Surg, Ahvaz, Iran

[10] Ahvaz Jundishapur Univ Med Sci, Fertil Infertil & Perinatol Res Ctr, Ahvaz, Iran

来源：

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY | 2023年 / 149卷 / 01期

关键词：

Retinoblastoma; Long non-coding RNA; Biomarker; Oncogene; Tumor suppressor; CANCER-CELL-PROLIFERATION; POOR-PROGNOSIS; AGGRAVATES RETINOBLASTOMA; PROMOTES PROLIFERATION; MALIGNANT PHENOTYPE; COLORECTAL-CANCER; CHEMO-RESISTANCE; MESSENGER-RNA; PROGRESSION; INVASION;

D O I：

10.1007/s00432-022-04398-z

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Introduction Retinoblastoma (RB) is the most common childhood tumor that can occur in the retina and develop in a sporadic or heritable form. Although various traditional treatment options have been used for patients with RB, identifying novel strategies for childhood cancers is necessary. Material and methods Recently, molecular-based targeted therapies have opened a greater therapeutic window for RB. Long non-coding RNAs (lncRNAs) presented a potential role as a biomarker for the detection of RB in various stages. Conclusion LncRNAs by targeting several miRNA/transcription factors play critical roles in the stimulation or suppression of RB. In this review, we summarized recent progress on the functions of tumor suppressors or oncogenes lncRNAs in RB.

引用

页码：401 / 421

页数：21

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