The effect of the COVID-19 pandemic on the treated incidence of psychotic disorders in South London

被引：2

作者：

Spinazzola, Edoardo ^{[1
]}

Meyer, Zeryab ^{[1
]}

Gray, Zoe Isabella ^{[2
]}

Azlan, Aryn ^{[1
]}

Wratten, Camille ^{[3
]}

Rayat, Mandeep ^{[1
]}

Hiscott, Lauren ^{[1
]}

Kyriakou, Loui ^{[4
]}

Cottrell, Dominic ^{[5
]}

Pritchard, Megan ^{[5
]}

da Costa, Mariana Pinto ^{[5
,6
,7
]}

Quattrone, Andrea ^{[5
,6
]}

Stewart, Robert ^{[5
,7
,8
,9
]}

Di Forti, Marta ^{[5
,8
,9
,10
]}

Murray, Robin MacGregor ^{[1
,5
,8
,9
]}

Quattrone, Diego ^{[5
,8
,9
,10
]}

机构：

[1] Kings Coll London, Dept Psychosis Studies, Inst Psychiat Psychol & Neurosci, London, England

[2] Avon & Wiltshire Mental Hlth Partnership NHS Trust, Bath, England

[3] South West London & St Georges Mental Hlth NHS Tru, London, England

[4] Hertfordshire Partnership Univ NHS Fdn Trust, St Albans, England

[5] South London & Maudsley NHS Fdn Trust, London, England

[6] Univ Porto, Inst Biomed Sci Abel Salazar, Porto, Portugal

[7] Inst Psychiat Psychol & Neurosci, Kings Coll London, Dept Psychol Med, London, England

[8] South London & Maudsley NHS Fdn Trust, Natl Inst Hlth & Care Res, Maudsley Biomed Res Ctr, London, England

[9] Kings Coll London, London, England

[10] Inst Psychiat Psychol & Neurosci, Kings Coll London, Social Genet & Dev Psychiat Ctr, London, England

来源：

PSYCHIATRY RESEARCH | 2023年 / 329卷

基金：

英国医学研究理事会;

关键词：

COVID-19; Psychotic disorders; Incidence; Schizophrenia; SCHIZOPHRENIA; DEPRESSION; ANXIETY; HEALTH;

D O I：

10.1016/j.psychres.2023.115483

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Evidence on the impact of the COVID-19 pandemic on psychotic disorders is so far scarce. We conducted an incidence study to ascertain rates of first-episode psychosis (FEP) before and during the COVID-19 pandemic in South London.We screened clinical records of individuals living in the London boroughs of Southwark and Lambeth who were referred to the early intervention services before (from 1/3/2019 to 28/2/2020) and during (from 1/3/ 2020 to 28/2/2021) the COVID-19 pandemic. We used the Office for National Statistics to determine the population at risk. We computed crude and sex-age standardised FEP incidence per 100,000 person-years. We used Poisson regression to calculate the incidence rate ratio (IRR) across the COVID-19 pandemic.A total of 321 incident cases of FEP were identified during the COVID-19 pandemic, accounting for a crude rate of 69.8 (95% CI 62.1-77.4) per 100,000 person-years. The crude rate for the year before was 47.5 (95% CI 41.2-53.8). The incidence variation between the two years accounted for an adjusted IRR of 1.45 (95% CI 1.22-1.72). The pandemic was accompanied by a 45% spike in the rates of first-episode psychosis. This finding should inform public health research and demonstrate the need for adequate resources for secondary care.

引用

页数：7