Biocompatible Hydrogels Based on Biodegradable Polyesters and Their Copolymers

被引:5
作者
Fomina, Yu. S. [1 ]
Semkina, A. S. [1 ,2 ]
Zagoskin, Yu. D. [1 ]
Aleksanyan, M. M. [3 ]
Chvalun, S. N. [1 ,2 ]
Grigoriev, T. E. [1 ]
机构
[1] Natl Res Ctr, Kurchatov Inst, Moscow 123182, Russia
[2] Russian Acad Sci, Enikolopov Inst Synthet Polymer Mat, Moscow 117393, Russia
[3] Petrovsky Russian Sci Ctr Surg, Moscow 119991, Russia
关键词
hydrogels; amphiphilic block copolymers; self-assembly; polylactide; polylactide-co-glycolide; polyethylene glycol; PLGA-PEG-PLGA; ABA TRIBLOCK COPOLYMERS; TEMPERATURE-SENSITIVE HYDROGEL; BLOCK-COPOLYMERS; DELIVERY-SYSTEM; MOLECULAR-WEIGHT; DRUG-DELIVERY; IN-VITRO; POLY(L-LACTIC ACID); AQUEOUS-SOLUTIONS;
D O I
10.1134/S1061933X23600756
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Poly(ethylene glycol)-based hydrogels have long proved to be promising materials for various biomedical technologies. This review considers systems based on the most common and studied copolymers of poly(ethylene glycol) and biodegradable polyesters of lactide and glycolide. Traditional and modern approaches to the synthesis of the copolymers and the production of hydrogels have been considered, the studies of the structure and properties of the materials have been analyzed, and the main directions of the application of these products in practice have been described.
引用
收藏
页码:795 / 816
页数:22
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