Sotrovimab Treatment for COVID-19 Effective in a B-Cell-Depleted Patient After Anti-CD20 Treatment

被引：0

作者：

Murase, Kazuyuki ^{[1
]}

Takada, Kohichi ^{[1
]}

Arihara, Yohei ^{[1
]}

Miyanishi, Koji ^{[1
]}

Kato, Junji ^{[2
]}

机构：

[1] Sapporo Med Univ, Dept Med Oncol, Sapporo, Japan

[2] Sapporo Kiyota Hosp, Dept Med Oncol, Sapporo, Japan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 07期

关键词：

sotrovimab; hematologic malignancy; anti-cd20; treatment; b cell depletion; covid-19; RITUXIMAB; VACCINE; RECONSTITUTION; LYMPHOMA; THERAPY;

D O I：

10.7759/cureus.41486

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with hematologic malignancies are well known to have prolonged COVID-19 pneumonia. The cause has been reported to be B cell depletion after administration of anti-CD20 antibodies. Here, we report a case of COVID-19 pneumonia due to prolonged B-cell depletion after anti-CD20 antibody therapy for malignant lymphoma two years before. Sotrovimab, a neutralizing antibody that was designed to prevent the progression of COVID-19, was successful in preventing the progression to severe disease in this B-cell -depleted patient.

引用

页数：3

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