Axillary Hidradenitis Suppurativa: A Comparison between Two Perforator Flap Reconstructive Approaches after Radical Surgical Management

被引:6
作者
Alabdulkareem, Mohammad [1 ,2 ]
Berkane, Yanis [1 ,3 ,4 ,5 ,8 ]
Le Bras, Enna [1 ]
Rousson, Etienne [1 ]
Chrelias, Theodoros [1 ]
Beaufils, Tristan [1 ]
Leclere, Franck-Marie [6 ,7 ]
Watier, Eric [1 ]
Bertheuil, Nicolas [1 ,3 ,8 ]
机构
[1] Univ Rennes, Dept Plast Reconstruct & Aesthet Surg, CHU Rennes, Rennes, France
[2] Majmaah Univ, Coll Med, Dept Surg, Al Majmaah, Saudi Arabia
[3] Rennes Univ Hosp, UMR U1236, MICMAC, Immunol & Cell Therapy Lab, Rennes, France
[4] Harvard Med Sch, Massachusetts Gen Hosp, Vascularized Composite Allotransplantat Lab, Boston, MA USA
[5] Harvard Med Sch, Shriners Childrens Boston, Boston, MA USA
[6] CHU Poitiers, Dept Plast Reconstruct & Hand Surg, F-86021 Poitiers, France
[7] Univ Poitiers, Lab Anat & Simulat, Poitiers, France
[8] CHU Rennes, Dept Plast Reconstruct & Aesthet Surg, 16 Blvd Bulgarie, F-35000 Rennes, France
关键词
INFLIXIMAB; EFFICACY; PATHOGENESIS; ADALIMUMAB; MODERATE; SURGERY; MUSCLE; TRIAL;
D O I
10.1097/GOX.0000000000005301
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background:Axillary hidradenitis suppurativa (HS) can result in significant functional impairment in both personal and professional lives. Stage 3 HS requires radical surgical treatment. Flap reconstruction allows for faster healing and better functional and aesthetic outcomes. We compared the results of thoracodorsal artery perforator (TDAP) and propeller inner arm artery perforator (IAAP) flap reconstructions after radical surgical treatment of axillary HS.Methods:We conducted a retrospective study that included 13 consecutive patients who underwent stage 3 axillary HS treatment between August 2015 and January 2023. Seven patients underwent reconstruction by islanded TDAP flaps, whereas six patients underwent reconstruction by propeller IAAP flaps, with one patient undergoing bilateral reconstruction. The data collected from the patient records included age, gender, smoking status, body mass index, comorbidities, operative time, defect size, flap size, hospital stay, and complications.Results:Although not statistically significant (P = 0.1923), a higher rate of flap complications is reported here with propeller IAAP flaps (42.86 %), whereas islanded TDAP flaps had no flap complications (0%). We found a statistically significant difference in operative time (P = 0.0006), defect size (P = 0.0064), and flap size (P = 0.0012) between the two groups. All patients exhibited satisfactory functional and aesthetic outcomes. Fourteen flaps were performed in total; only one case exhibited recurrence (7.14%).Conclusion:After radical surgical management, both islanded TDAP and propeller IAAP flap reconstructions offer excellent outcomes for stage 3 axillary HS. We strongly encourage our peers to consider performing perforator flaps over secondary healing for these patients with a major functional impairment.
引用
收藏
页数:10
相关论文
共 55 条
[31]   Impaired Notch signalling: the unifying mechanism explaining the pathogenesis of hidradenitis suppurativa (acne inversa) [J].
Melnik, B. C. ;
Plewig, G. .
BRITISH JOURNAL OF DERMATOLOGY, 2013, 168 (04) :876-878
[32]  
Menderes A, 2010, INT J MED SCI, V7, P240
[33]   A double-blind placebo-controlled randomized trial of adalimumab in the treatment of hidradenitis suppurativa [J].
Miller, I. ;
Lynggaard, C. D. ;
Lophaven, S. ;
Zachariae, C. ;
Dufour, D. N. ;
Jemec, G. B. E. .
BRITISH JOURNAL OF DERMATOLOGY, 2011, 165 (02) :391-398
[34]   The Burden of Hidradenitis Suppurativa Signs and Symptoms in Quality of Life: Systematic Review and Meta-Analysis [J].
Montero-Vilchez, Trinidad ;
Diaz-Calvillo, Pablo ;
Rodriguez-Pozo, Juan-Angel ;
Cuenca-Barrales, Carlos ;
Martinez-Lopez, Antonio ;
Arias-Santiago, Salvador ;
Molina-Leyva, Alejandro .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2021, 18 (13)
[35]   Four-weekly infliximab in the treatment of severe hidradenitis suppurativa [J].
Moriarty, B. ;
Jiyad, Z. ;
Creamer, D. .
BRITISH JOURNAL OF DERMATOLOGY, 2014, 170 (04) :986-987
[36]   A DOUBLE-BLIND CONTROLLED CROSSOVER TRIAL OF CYPROTERONE-ACETATE IN FEMALES WITH HIDRADENITIS SUPPURATIVA [J].
MORTIMER, PS ;
DAWBER, RPR ;
GALES, MA ;
MOORE, RA .
BRITISH JOURNAL OF DERMATOLOGY, 1986, 115 (03) :263-268
[37]   Evaluation of the mobility of the shoulder and quality of life after perforator flaps for recalcitrant axillary hidradenitis [J].
Nail-Barthelemy, R. ;
Stroumza, N. ;
Qassemyar, Q. ;
Delage, M. ;
Nassif, A. ;
Atlan, M. .
ANNALES DE CHIRURGIE PLASTIQUE ESTHETIQUE, 2019, 64 (01) :68-77
[38]   Pathogenesis and pharmacotherapy of Hidradenitis suppurativa [J].
Nazary, Maiwand ;
van der Zee, H. H. ;
Prens, E. P. ;
Folkerts, Gert ;
Boer, Jurr .
EUROPEAN JOURNAL OF PHARMACOLOGY, 2011, 672 (1-3) :1-8
[39]  
Nesbitt Emily, 2020, Int J Womens Dermatol, V6, P80, DOI 10.1016/j.ijwd.2019.11.004
[40]   Perforator-based propeller flaps for leg reconstruction in pediatric patients [J].
Ozalp, Burhan ;
Aydinol, Mustafa .
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY, 2016, 69 (10) :E205-E211